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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAA1
All Species:
35.76
Human Site:
T252
Identified Species:
60.51
UniProt:
P09110
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09110
NP_001123882.1
424
44292
T252
D
E
G
I
R
P
S
T
T
M
E
G
L
A
K
Chimpanzee
Pan troglodytes
XP_001171310
424
44347
T252
D
E
G
I
R
P
S
T
T
M
E
G
L
A
K
Rhesus Macaque
Macaca mulatta
XP_001088834
424
44308
T252
D
E
G
I
R
P
S
T
T
M
E
G
L
A
K
Dog
Lupus familis
XP_534222
426
44065
T254
D
E
G
I
R
P
N
T
T
M
E
G
L
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCH0
424
43977
T252
D
E
G
V
R
P
S
T
T
M
Q
G
L
A
K
Rat
Rattus norvegicus
P07871
424
43802
T252
D
E
G
V
R
P
S
T
T
M
E
G
L
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232577
426
43945
T260
D
E
G
V
R
P
S
T
T
L
E
G
L
A
K
Frog
Xenopus laevis
NP_001080604
419
43740
T247
D
E
G
V
R
A
S
T
T
M
E
G
L
S
R
Zebra Danio
Brachydanio rerio
NP_001002207
418
43985
T246
D
D
G
I
R
P
G
T
T
L
E
G
L
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200436
367
38364
G211
K
P
A
F
S
P
E
G
T
T
T
A
G
N
S
Poplar Tree
Populus trichocarpa
XP_002299284
460
48692
E265
V
D
D
G
I
R
P
E
T
S
V
A
G
L
G
Maize
Zea mays
NP_001131193
461
47940
G266
V
D
D
G
I
R
P
G
T
T
A
S
G
L
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LF48
443
46593
N259
V
D
D
G
I
R
P
N
T
T
L
S
G
L
A
Baker's Yeast
Sacchar. cerevisiae
P27796
417
44712
A251
G
P
R
P
N
V
T
A
E
S
L
S
S
I
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.5
91.7
N.A.
85.8
87
N.A.
N.A.
78.6
73.5
72.4
N.A.
N.A.
N.A.
N.A.
59.4
Protein Similarity:
100
99.7
99
94.5
N.A.
92.4
93.4
N.A.
N.A.
88.7
86.3
83.2
N.A.
N.A.
N.A.
N.A.
70.9
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
86.6
73.3
80
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
93.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
52.1
52.9
N.A.
54.8
51.8
N.A.
Protein Similarity:
68.7
67.6
N.A.
71.3
65.5
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
0
N.A.
P-Site Similarity:
13.3
13.3
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
8
0
0
8
15
0
58
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
65
29
22
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
58
0
0
0
0
8
8
8
0
58
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
65
22
0
0
8
15
0
0
0
65
29
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
36
22
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
58
% K
% Leu:
0
0
0
0
0
0
0
0
0
15
15
0
65
22
0
% L
% Met:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
8
0
0
0
0
0
8
0
% N
% Pro:
0
15
0
8
0
65
22
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
8
0
65
22
0
0
0
0
0
0
0
0
15
% R
% Ser:
0
0
0
0
8
0
50
0
0
15
0
22
8
8
8
% S
% Thr:
0
0
0
0
0
0
8
65
93
22
8
0
0
0
0
% T
% Val:
22
0
0
29
0
8
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _