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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAA1
All Species:
43.94
Human Site:
T46
Identified Species:
74.36
UniProt:
P09110
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09110
NP_001123882.1
424
44292
T46
V
V
V
H
G
R
R
T
A
I
C
R
A
G
R
Chimpanzee
Pan troglodytes
XP_001171310
424
44347
T46
V
V
V
H
G
R
R
T
A
I
C
R
A
G
R
Rhesus Macaque
Macaca mulatta
XP_001088834
424
44308
T46
V
V
V
H
G
R
R
T
A
I
C
R
A
G
R
Dog
Lupus familis
XP_534222
426
44065
T48
V
V
V
H
G
R
R
T
A
I
G
R
G
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCH0
424
43977
T46
V
V
V
H
G
R
R
T
P
I
G
R
A
S
R
Rat
Rattus norvegicus
P07871
424
43802
T46
V
V
V
H
G
R
R
T
P
I
G
R
A
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232577
426
43945
T54
V
V
V
H
G
R
R
T
A
I
G
R
A
K
R
Frog
Xenopus laevis
NP_001080604
419
43740
T41
V
I
V
A
G
R
R
T
P
I
C
K
A
K
R
Zebra Danio
Brachydanio rerio
NP_001002207
418
43985
T40
V
V
V
H
G
L
R
T
A
I
G
R
A
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200436
367
38364
V31
D
R
L
G
D
I
V
V
G
N
V
L
L
P
G
Poplar Tree
Populus trichocarpa
XP_002299284
460
48692
T58
V
I
V
A
A
Y
R
T
P
Q
C
K
S
K
R
Maize
Zea mays
NP_001131193
461
47940
T59
V
V
V
A
A
Y
R
T
P
I
C
K
A
K
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LF48
443
46593
T52
V
I
V
A
A
Q
R
T
A
L
C
K
A
K
R
Baker's Yeast
Sacchar. cerevisiae
P27796
417
44712
S44
V
I
V
A
A
N
R
S
A
I
G
K
G
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.5
91.7
N.A.
85.8
87
N.A.
N.A.
78.6
73.5
72.4
N.A.
N.A.
N.A.
N.A.
59.4
Protein Similarity:
100
99.7
99
94.5
N.A.
92.4
93.4
N.A.
N.A.
88.7
86.3
83.2
N.A.
N.A.
N.A.
N.A.
70.9
P-Site Identity:
100
100
100
86.6
N.A.
80
86.6
N.A.
N.A.
86.6
66.6
80
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
80
86.6
N.A.
N.A.
86.6
80
80
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
52.1
52.9
N.A.
54.8
51.8
N.A.
Protein Similarity:
68.7
67.6
N.A.
71.3
65.5
N.A.
P-Site Identity:
40
60
N.A.
53.3
33.3
N.A.
P-Site Similarity:
60
66.6
N.A.
80
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
36
29
0
0
0
58
0
0
0
72
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
65
0
0
0
8
0
43
0
15
36
8
% G
% His:
0
0
0
58
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
29
0
0
0
8
0
0
0
79
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
36
0
43
8
% K
% Leu:
0
0
8
0
0
8
0
0
0
8
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
36
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
58
93
0
0
0
0
58
0
0
86
% R
% Ser:
0
0
0
0
0
0
0
8
0
0
0
0
8
8
0
% S
% Thr:
0
0
0
0
0
0
0
86
0
0
0
0
0
0
0
% T
% Val:
93
65
93
0
0
0
8
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _