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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACAA1
All Species:
22.73
Human Site:
Y402
Identified Species:
38.46
UniProt:
P09110
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09110
NP_001123882.1
424
44292
Y402
K
R
R
G
K
R
A
Y
G
V
V
S
M
C
I
Chimpanzee
Pan troglodytes
XP_001171310
424
44347
Y402
K
R
R
G
K
R
A
Y
G
V
V
S
M
C
I
Rhesus Macaque
Macaca mulatta
XP_001088834
424
44308
Y402
K
R
R
G
K
R
A
Y
G
V
V
S
M
C
I
Dog
Lupus familis
XP_534222
426
44065
Y404
K
R
R
G
K
R
A
Y
G
V
V
S
M
C
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCH0
424
43977
Y402
K
R
R
G
R
R
A
Y
G
V
V
S
M
C
I
Rat
Rattus norvegicus
P07871
424
43802
Y402
K
R
R
G
R
R
A
Y
G
V
V
S
M
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232577
426
43945
E401
Q
V
V
T
L
L
N
E
L
K
R
R
G
K
R
Frog
Xenopus laevis
NP_001080604
419
43740
F397
K
R
R
G
K
R
G
F
G
V
V
S
M
C
I
Zebra Danio
Brachydanio rerio
NP_001002207
418
43985
F396
K
R
R
R
K
R
G
F
G
V
V
S
M
C
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200436
367
38364
G346
R
R
G
N
R
A
Y
G
V
V
S
M
C
I
G
Poplar Tree
Populus trichocarpa
XP_002299284
460
48692
R416
K
R
R
G
R
D
C
R
F
G
V
V
S
M
C
Maize
Zea mays
NP_001131193
461
47940
R417
K
R
R
G
R
D
C
R
F
G
V
V
T
M
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LF48
443
46593
R410
K
R
R
G
K
D
C
R
F
G
V
V
S
M
C
Baker's Yeast
Sacchar. cerevisiae
P27796
417
44712
I388
G
A
R
Q
V
A
T
I
L
R
E
L
K
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.5
91.7
N.A.
85.8
87
N.A.
N.A.
78.6
73.5
72.4
N.A.
N.A.
N.A.
N.A.
59.4
Protein Similarity:
100
99.7
99
94.5
N.A.
92.4
93.4
N.A.
N.A.
88.7
86.3
83.2
N.A.
N.A.
N.A.
N.A.
70.9
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
0
86.6
80
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
93.3
86.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
52.1
52.9
N.A.
54.8
51.8
N.A.
Protein Similarity:
68.7
67.6
N.A.
71.3
65.5
N.A.
P-Site Identity:
33.3
33.3
N.A.
40
6.6
N.A.
P-Site Similarity:
40
40
N.A.
40
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
15
43
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
22
0
0
0
0
0
8
58
22
% C
% Asp:
0
0
0
0
0
22
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
15
22
0
0
0
0
0
0
% F
% Gly:
8
0
8
72
0
0
15
8
58
22
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
58
% I
% Lys:
79
0
0
0
50
0
0
0
0
8
0
0
8
15
0
% K
% Leu:
0
0
0
0
8
8
0
0
15
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
58
22
0
% M
% Asn:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
86
86
8
36
58
0
22
0
8
8
8
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
8
58
15
0
0
% S
% Thr:
0
0
0
8
0
0
8
0
0
0
0
0
8
0
0
% T
% Val:
0
8
8
0
8
0
0
0
8
65
79
22
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
43
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _