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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DBH
All Species:
20
Human Site:
Y249
Identified Species:
44
UniProt:
P09172
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09172
NP_000778.3
617
69065
Y249
S
R
H
H
I
I
K
Y
E
P
I
V
T
K
G
Chimpanzee
Pan troglodytes
XP_520341
617
68924
Y249
S
R
H
H
I
I
K
Y
E
P
I
V
T
K
G
Rhesus Macaque
Macaca mulatta
XP_001100196
603
67800
Y235
P
Q
H
H
I
V
K
Y
E
P
I
I
T
K
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64237
621
70168
Y253
P
R
H
H
I
I
M
Y
E
A
I
V
T
E
G
Rat
Rattus norvegicus
Q05754
620
69857
Y252
P
R
H
H
I
I
M
Y
E
A
I
V
T
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505587
619
70203
Y250
P
R
H
H
I
V
M
Y
E
P
V
I
T
E
G
Chicken
Gallus gallus
Q98ST7
614
69485
H235
K
D
H
E
N
L
V
H
H
I
L
L
Y
Q
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5TZ24
614
69327
H237
K
G
H
E
N
L
V
H
H
I
L
L
Y
Q
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q86B61
670
77711
Q300
R
R
R
H
H
I
V
Q
F
E
P
L
I
R
T
Honey Bee
Apis mellifera
NP_001071292
613
70078
L247
N
A
W
Q
L
E
I
L
T
D
R
V
K
V
P
Nematode Worm
Caenorhab. elegans
Q9XTQ6
585
66735
P233
R
M
E
P
Y
V
T
P
G
N
E
H
L
V
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
89.1
N.A.
N.A.
78.7
77
N.A.
73.1
32.2
N.A.
29.8
N.A.
34.4
40.5
34.5
N.A.
Protein Similarity:
100
99.8
93.3
N.A.
N.A.
87.7
85.6
N.A.
84.3
49.4
N.A.
48.9
N.A.
50.1
56.5
54.6
N.A.
P-Site Identity:
100
100
73.3
N.A.
N.A.
73.3
73.3
N.A.
60
6.6
N.A.
6.6
N.A.
20
6.6
0
N.A.
P-Site Similarity:
100
100
93.3
N.A.
N.A.
80
80
N.A.
86.6
40
N.A.
40
N.A.
33.3
20
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
19
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% C
% Asp:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
10
19
0
10
0
0
55
10
10
0
0
28
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
55
% G
% His:
0
0
73
64
10
0
0
19
19
0
0
10
0
0
10
% H
% Ile:
0
0
0
0
55
46
10
0
0
19
46
19
10
0
0
% I
% Lys:
19
0
0
0
0
0
28
0
0
0
0
0
10
28
0
% K
% Leu:
0
0
0
0
10
19
0
10
0
0
19
28
10
0
0
% L
% Met:
0
10
0
0
0
0
28
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
19
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
37
0
0
10
0
0
0
10
0
37
10
0
0
0
10
% P
% Gln:
0
10
0
10
0
0
0
10
0
0
0
0
0
19
0
% Q
% Arg:
19
55
10
0
0
0
0
0
0
0
10
0
0
10
0
% R
% Ser:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
10
0
0
0
55
0
10
% T
% Val:
0
0
0
0
0
28
28
0
0
0
10
46
0
19
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
55
0
0
0
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _