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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CST2
All Species:
14.55
Human Site:
S53
Identified Species:
40
UniProt:
P09228
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09228
NP_001313.1
141
16445
S53
R
A
L
H
F
V
I
S
E
Y
N
K
A
T
E
Chimpanzee
Pan troglodytes
XP_514555
141
16331
S53
R
A
L
H
F
A
I
S
E
Y
N
K
A
T
E
Rhesus Macaque
Macaca mulatta
O19092
146
15839
S58
R
A
L
D
F
A
V
S
E
Y
N
K
A
S
N
Dog
Lupus familis
XP_848294
141
16619
K53
Q
A
L
W
Y
A
M
K
E
Y
N
K
A
S
K
Cat
Felis silvestris
Mouse
Mus musculus
P21460
140
15512
S52
R
A
L
D
F
A
V
S
E
Y
N
K
G
S
N
Rat
Rattus norvegicus
P14841
140
15418
S52
R
A
L
D
F
A
V
S
E
Y
N
K
G
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518631
78
8921
Chicken
Gallus gallus
P01038
139
15268
A53
R
A
L
Q
F
A
M
A
E
Y
N
R
A
S
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001026843
128
14125
N46
Q
F
A
M
A
Q
Y
N
R
Q
S
N
D
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.9
57.5
27.6
N.A.
54.6
52.4
N.A.
27.6
38.2
N.A.
28.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95
70.5
53.1
N.A.
70.9
70.9
N.A.
41.1
61.7
N.A.
51.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
66.6
46.6
N.A.
60
60
N.A.
0
53.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
80
80
N.A.
73.3
73.3
N.A.
0
80
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
78
12
0
12
67
0
12
0
0
0
0
56
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
34
0
0
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
78
0
0
0
0
0
23
% E
% Phe:
0
12
0
0
67
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% G
% His:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
0
0
67
0
0
12
% K
% Leu:
0
0
78
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
12
0
0
23
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
78
12
0
0
45
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
23
0
0
12
0
12
0
0
0
12
0
0
0
0
0
% Q
% Arg:
67
0
0
0
0
0
0
0
12
0
0
12
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
56
0
0
12
0
0
56
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% T
% Val:
0
0
0
0
0
12
34
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
12
0
0
78
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _