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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CST2 All Species: 21.21
Human Site: T92 Identified Species: 58.33
UniProt: P09228 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09228 NP_001313.1 141 16445 T92 F D I E V G R T I C T K S Q P
Chimpanzee Pan troglodytes XP_514555 141 16331 T92 F D V E V G R T I C T K S Q P
Rhesus Macaque Macaca mulatta O19092 146 15839 T97 L D V E L G R T T C T K T Q P
Dog Lupus familis XP_848294 141 16619 T92 L E V K I A R T M C K K I S G
Cat Felis silvestris
Mouse Mus musculus P21460 140 15512 T91 L D V E M G R T T C T K S Q T
Rat Rattus norvegicus P14841 140 15418 T91 L D V E M G R T T C T K S Q T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518631 78 8921 C31 V E I G R T T C T K S V S D L
Chicken Gallus gallus P01038 139 15268 T92 L Q V E I G R T T C P K S S G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001026843 128 14125 R81 I F T V D V A R T T C R K G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.9 57.5 27.6 N.A. 54.6 52.4 N.A. 27.6 38.2 N.A. 28.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 95 70.5 53.1 N.A. 70.9 70.9 N.A. 41.1 61.7 N.A. 51.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 66.6 26.6 N.A. 66.6 66.6 N.A. 13.3 46.6 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 60 N.A. 80 80 N.A. 26.6 60 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 12 12 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 12 0 78 12 0 0 0 0 % C
% Asp: 0 56 0 0 12 0 0 0 0 0 0 0 0 12 0 % D
% Glu: 0 23 0 67 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 23 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 12 0 67 0 0 0 0 0 0 0 12 34 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 23 0 23 0 0 0 23 0 0 0 12 0 0 % I
% Lys: 0 0 0 12 0 0 0 0 0 12 12 78 12 0 0 % K
% Leu: 56 0 0 0 12 0 0 0 0 0 0 0 0 0 12 % L
% Met: 0 0 0 0 23 0 0 0 12 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 34 % P
% Gln: 0 12 0 0 0 0 0 0 0 0 0 0 0 56 0 % Q
% Arg: 0 0 0 0 12 0 78 12 0 0 0 12 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 12 0 67 23 0 % S
% Thr: 0 0 12 0 0 12 12 78 67 12 56 0 12 0 23 % T
% Val: 12 0 67 12 23 12 0 0 0 0 0 12 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _