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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAEP All Species: 12.42
Human Site: T67 Identified Species: 30.37
UniProt: P09466 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09466 NP_001018059.1 180 20624 T67 H I T S L L P T P E D N L E I
Chimpanzee Pan troglodytes P61641 201 22991 S72 V D E T G Q M S A T A K G R V
Rhesus Macaque Macaca mulatta NP_001028099 180 20798 T67 H V T S L W P T P E D H L E I
Dog Lupus familis XP_548384 214 24112 T102 Y I Q E L R P T P Q D N L E I
Cat Felis silvestris
Mouse Mus musculus P02762 180 20631 L66 F L E Q I H V L E N S L V L K
Rat Rattus norvegicus P02761 181 20718 E68 M Q H I D V L E N S L G F K F
Wallaby Macropus eugenll Q29614 174 20201 E65 K E V N L T P E G N L E L V L
Platypus Ornith. anatinus XP_001507062 282 31489 N66 F K T V T P Q N T K E L I I T
Chicken Gallus gallus P41263 196 22497 S75 V D E N G Q M S A T A K G R V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038878 184 20627 T66 G T A M L V P T E E G D L E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.3 83.3 49 N.A. 25.5 26.5 29.4 21.2 22.9 N.A. 24.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 38.3 90 62.1 N.A. 44.4 44.2 56.1 37.9 39.2 N.A. 45.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 80 66.6 N.A. 0 0 20 6.6 0 N.A. 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 93.3 80 N.A. 20 13.3 33.3 26.6 20 N.A. 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 20 0 20 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 20 0 0 10 0 0 0 0 0 30 10 0 0 0 % D
% Glu: 0 10 30 10 0 0 0 20 20 30 10 10 0 40 0 % E
% Phe: 20 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % F
% Gly: 10 0 0 0 20 0 0 0 10 0 10 10 20 0 0 % G
% His: 20 0 10 0 0 10 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 20 0 10 10 0 0 0 0 0 0 0 10 10 30 % I
% Lys: 10 10 0 0 0 0 0 0 0 10 0 20 0 10 10 % K
% Leu: 0 10 0 0 50 10 10 10 0 0 20 20 50 10 20 % L
% Met: 10 0 0 10 0 0 20 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 20 0 0 0 10 10 20 0 20 0 0 0 % N
% Pro: 0 0 0 0 0 10 50 0 30 0 0 0 0 0 0 % P
% Gln: 0 10 10 10 0 20 10 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 0 0 20 0 % R
% Ser: 0 0 0 20 0 0 0 20 0 10 10 0 0 0 0 % S
% Thr: 0 10 30 10 10 10 0 40 10 20 0 0 0 0 10 % T
% Val: 20 10 10 10 0 20 10 0 0 0 0 0 10 10 20 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _