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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNAO1
All Species:
43.33
Human Site:
Y69
Identified Species:
95.33
UniProt:
P09471
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09471
NP_066268.1
354
40051
Y69
S
G
E
D
V
K
Q
Y
K
P
V
V
Y
S
N
Chimpanzee
Pan troglodytes
XP_510976
537
58898
Y252
S
G
E
D
V
K
Q
Y
K
P
V
V
Y
S
N
Rhesus Macaque
Macaca mulatta
XP_001096035
571
62486
Y286
S
G
E
D
V
K
Q
Y
K
P
V
V
Y
S
N
Dog
Lupus familis
XP_863178
354
40114
Y69
S
G
E
D
V
K
Q
Y
K
P
V
V
Y
S
N
Cat
Felis silvestris
Mouse
Mus musculus
P18872
354
40066
Y69
S
G
E
D
V
K
Q
Y
K
P
V
V
Y
S
N
Rat
Rattus norvegicus
P59215
354
40050
Y69
S
G
E
D
V
K
Q
Y
K
P
V
V
Y
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P50146
354
40360
Y69
S
E
E
E
C
K
Q
Y
K
A
V
V
Y
S
N
Frog
Xenopus laevis
P10825
354
40445
Y69
S
G
E
D
V
K
Q
Y
K
P
V
V
Y
S
N
Zebra Danio
Brachydanio rerio
NP_957081
354
39958
Y69
S
G
D
D
V
K
Q
Y
K
P
V
V
Y
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16378
354
40457
Y69
T
A
E
D
F
K
Q
Y
R
P
V
V
Y
S
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51875
354
40433
Y69
T
A
E
D
Y
K
Q
Y
K
P
V
V
Y
S
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.9
62
98.3
N.A.
98
98.5
N.A.
N.A.
72
90.1
95.7
N.A.
82.1
N.A.
82.1
N.A.
Protein Similarity:
100
65.9
62
99.1
N.A.
98.5
99.1
N.A.
N.A.
83
94.9
98.8
N.A.
89.8
N.A.
90.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
73.3
100
93.3
N.A.
73.3
N.A.
80
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
80
100
100
N.A.
86.6
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
91
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
91
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
73
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
100
0
0
91
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% N
% Pro:
0
0
0
0
0
0
0
0
0
91
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
82
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% S
% Thr:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
73
0
0
0
0
0
100
100
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
100
0
0
0
0
100
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _