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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNAO1 All Species: 45.15
Human Site: Y74 Identified Species: 99.33
UniProt: P09471 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09471 NP_066268.1 354 40051 Y74 K Q Y K P V V Y S N T I Q S L
Chimpanzee Pan troglodytes XP_510976 537 58898 Y257 K Q Y K P V V Y S N T I Q S L
Rhesus Macaque Macaca mulatta XP_001096035 571 62486 Y291 K Q Y K P V V Y S N T I Q S L
Dog Lupus familis XP_863178 354 40114 Y74 K Q Y K P V V Y S N T I Q S L
Cat Felis silvestris
Mouse Mus musculus P18872 354 40066 Y74 K Q Y K P V V Y S N T I Q S L
Rat Rattus norvegicus P59215 354 40050 Y74 K Q Y K P V V Y S N T I Q S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P50146 354 40360 Y74 K Q Y K A V V Y S N T I Q S I
Frog Xenopus laevis P10825 354 40445 Y74 K Q Y K P V V Y S N T I Q S L
Zebra Danio Brachydanio rerio NP_957081 354 39958 Y74 K Q Y K P V V Y S N T I Q S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16378 354 40457 Y74 K Q Y R P V V Y S N T I Q S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P51875 354 40433 Y74 K Q Y K P V V Y S N T V Q S L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.9 62 98.3 N.A. 98 98.5 N.A. N.A. 72 90.1 95.7 N.A. 82.1 N.A. 82.1 N.A.
Protein Similarity: 100 65.9 62 99.1 N.A. 98.5 99.1 N.A. N.A. 83 94.9 98.8 N.A. 89.8 N.A. 90.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 86.6 100 100 N.A. 93.3 N.A. 93.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 100 100 N.A. 100 N.A. 100 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 91 0 0 10 % I
% Lys: 100 0 0 91 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % N
% Pro: 0 0 0 0 91 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 100 0 0 0 0 0 0 0 0 0 0 100 0 0 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 100 0 0 0 0 100 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % T
% Val: 0 0 0 0 0 100 100 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 100 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _