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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPARC All Species: 39.7
Human Site: Y179 Identified Species: 79.39
UniProt: P09486 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09486 NP_003109.1 303 34632 Y179 K N V L V T L Y E R D E D N N
Chimpanzee Pan troglodytes XP_001168430 245 27917 L160 P P C L D S E L T E F P L R M
Rhesus Macaque Macaca mulatta XP_001101364 572 63748 Y283 K N V L V T L Y E R D E D N N
Dog Lupus familis XP_854982 303 34538 Y179 K N V L V T L Y E R D E D N N
Cat Felis silvestris
Mouse Mus musculus P07214 302 34432 Y178 K N V L V T L Y E R D E G N N
Rat Rattus norvegicus P16975 301 34277 Y177 K N V L V T L Y E R D E G N N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510554 302 34451 Y178 K N V M V T L Y E R D E G N N
Chicken Gallus gallus P36377 298 34042 Y174 K N V L I T L Y E R D E D N N
Frog Xenopus laevis P36378 300 34577 Y176 K N V L V S L Y E R D E N N N
Zebra Danio Brachydanio rerio NP_001001942 291 33415 Y167 K N V L V T L Y E R D E D N N
Tiger Blowfish Takifugu rubipres NP_001027722 298 34096 Y174 K N V L V T L Y E R D M D N N
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34714 264 30154 F158 E R M A D W L F Q V M K E L K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.8 52.2 97.3 N.A. 92.4 92.4 N.A. 93 85.1 77.8 77.8 74.2 N.A. N.A. 33.3 N.A.
Protein Similarity: 100 80.8 52.4 98.6 N.A. 95.7 95.7 N.A. 95.7 91.7 89.7 87.1 85.4 N.A. N.A. 52.1 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 93.3 93.3 N.A. 86.6 93.3 86.6 100 93.3 N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 93.3 93.3 N.A. 93.3 100 100 100 93.3 N.A. N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 17 0 0 0 0 0 84 0 50 0 0 % D
% Glu: 9 0 0 0 0 0 9 0 84 9 0 75 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 84 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % K
% Leu: 0 0 0 84 0 0 92 9 0 0 0 0 9 9 0 % L
% Met: 0 0 9 9 0 0 0 0 0 0 9 9 0 0 9 % M
% Asn: 0 84 0 0 0 0 0 0 0 0 0 0 9 84 84 % N
% Pro: 9 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 0 9 0 0 0 0 0 0 0 84 0 0 0 9 0 % R
% Ser: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 75 0 0 9 0 0 0 0 0 0 % T
% Val: 0 0 84 0 75 0 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 84 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _