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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPARC
All Species:
40
Human Site:
Y224
Identified Species:
80
UniProt:
P09486
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09486
NP_003109.1
303
34632
Y224
A
R
D
F
E
K
N
Y
N
M
Y
I
F
P
V
Chimpanzee
Pan troglodytes
XP_001168430
245
27917
N185
L
Y
E
R
D
E
D
N
N
L
L
T
E
K
Q
Rhesus Macaque
Macaca mulatta
XP_001101364
572
63748
Y328
A
R
D
F
E
K
N
Y
N
M
Y
I
F
P
V
Dog
Lupus familis
XP_854982
303
34538
Y224
A
R
D
F
E
K
N
Y
N
M
Y
I
F
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P07214
302
34432
Y223
A
R
D
F
E
K
N
Y
N
M
Y
I
F
P
V
Rat
Rattus norvegicus
P16975
301
34277
Y222
A
R
D
F
E
K
N
Y
N
M
Y
I
F
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510554
302
34451
Y223
A
R
D
F
E
K
N
Y
N
M
Y
I
F
P
V
Chicken
Gallus gallus
P36377
298
34042
Y219
A
R
D
F
E
K
N
Y
N
M
Y
I
F
P
V
Frog
Xenopus laevis
P36378
300
34577
Y221
V
R
D
F
E
K
N
Y
N
M
Y
I
F
P
V
Zebra Danio
Brachydanio rerio
NP_001001942
291
33415
Y212
A
L
D
F
E
K
N
Y
N
M
Y
I
F
P
V
Tiger Blowfish
Takifugu rubipres
NP_001027722
298
34096
Y219
A
H
D
F
K
K
N
Y
N
M
Y
I
F
P
V
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34714
264
30154
E187
S
E
A
E
N
D
D
E
K
K
H
V
Y
P
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.8
52.2
97.3
N.A.
92.4
92.4
N.A.
93
85.1
77.8
77.8
74.2
N.A.
N.A.
33.3
N.A.
Protein Similarity:
100
80.8
52.4
98.6
N.A.
95.7
95.7
N.A.
95.7
91.7
89.7
87.1
85.4
N.A.
N.A.
52.1
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
100
100
93.3
93.3
86.6
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
100
100
93.3
93.3
93.3
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
75
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
84
0
9
9
17
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
9
9
75
9
0
9
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
84
0
0
0
0
0
0
0
0
84
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
84
0
0
0
% I
% Lys:
0
0
0
0
9
84
0
0
9
9
0
0
0
9
0
% K
% Leu:
9
9
0
0
0
0
0
0
0
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
84
9
92
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
92
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
67
0
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
92
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
84
0
0
84
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _