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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPM1 All Species: 30.91
Human Site: S36 Identified Species: 61.82
UniProt: P09493 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09493 NP_000357.3 284 32709 S36 K K A A E D R S K Q L E D E L
Chimpanzee Pan troglodytes XP_001173748 284 32708 S36 K K A A E D R S K Q L E D E L
Rhesus Macaque Macaca mulatta XP_001103704 284 32680 S36 K K A A E D R S K Q L E D E L
Dog Lupus familis XP_864907 284 32692 S36 K K A A E D R S K Q L E D E L
Cat Felis silvestris
Mouse Mus musculus P21107 284 32844 S36 Q K Q A E E R S K Q L E D E L
Rat Rattus norvegicus P58775 284 32818 C36 K K Q A E D R C K Q L E E E Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P19352 284 32758 C36 K K Q A E D R C K Q L E E E Q
Frog Xenopus laevis Q01173 284 32632 S36 K K G A E D K S K Q L E D E L
Zebra Danio Brachydanio rerio P13104 284 32704 S36 K K A A E E R S K Q L E D D L
Tiger Blowfish Takifugu rubipres NP_001027746 284 32727 S36 K K A A E D R S K Q H E D E L
Fruit Fly Dros. melanogaster P49455 518 54567 A36 A R D A N T R A E K A E E E A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22866 284 32985 V29 A D A A E E K V R Q I T E K L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.3 99.3 N.A. 90.4 85.9 N.A. N.A. 84.5 94 92.2 90.4 31 N.A. 58 N.A.
Protein Similarity: 100 100 100 99.6 N.A. 96.4 95.4 N.A. N.A. 95 97.8 97.1 96.4 41.8 N.A. 74.3 N.A.
P-Site Identity: 100 100 100 100 N.A. 80 73.3 N.A. N.A. 73.3 86.6 86.6 93.3 26.6 N.A. 33.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 80 N.A. N.A. 80 93.3 100 93.3 60 N.A. 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 59 100 0 0 0 9 0 0 9 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % C
% Asp: 0 9 9 0 0 67 0 0 0 0 0 0 67 9 0 % D
% Glu: 0 0 0 0 92 25 0 0 9 0 0 92 34 84 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 75 84 0 0 0 0 17 0 84 9 0 0 0 9 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 75 0 0 0 75 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 25 0 0 0 0 0 0 92 0 0 0 0 17 % Q
% Arg: 0 9 0 0 0 0 84 0 9 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 0 % T
% Val: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _