Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WNT2 All Species: 23.64
Human Site: S144 Identified Species: 52
UniProt: P09544 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09544 NP_003382.1 360 40418 S144 C D P K K M G S A K D S K G I
Chimpanzee Pan troglodytes Q2QLE7 360 40426 S144 C D P K K M G S A K D S K G I
Rhesus Macaque Macaca mulatta XP_001107861 391 43684 R175 C D P Y T R G R H H D Q R G D
Dog Lupus familis XP_854963 360 40149 T144 C D P K K K G T A K D S K G S
Cat Felis silvestris
Mouse Mus musculus P21552 360 40478 S144 C D P K K K G S A K D S K G T
Rat Rattus norvegicus Q9QXQ7 380 42265 K171 C S R A A R P K D L P R D W L
Wallaby Macropus eugenll
Platypus Ornith. anatinus Q07DZ8 361 40096 S145 C D P K K K G S A K D S K G T
Chicken Gallus gallus Q98SN7 385 42934 R169 C D P L K R G R A K D E R G E
Frog Xenopus laevis P87387 351 40101 R135 C D P K K R G R S K D E R G E
Zebra Danio Brachydanio rerio Q92048 350 39771 S142 C D P G K K G S S R D A K G A
Tiger Blowfish Takifugu rubipres NP_001163831 350 38935 S142 C D P A K K G S S R D A K G S
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 61.3 93 N.A. 96.1 46.5 N.A. 89.7 69.6 71.6 68.3 67.5 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 73.6 95.2 N.A. 97.5 60.5 N.A. 93 80.5 84.1 80.8 81.6 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 40 80 N.A. 86.6 6.6 N.A. 86.6 60 60 60 60 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 46.6 86.6 N.A. 86.6 13.3 N.A. 86.6 66.6 73.3 80 80 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 10 0 0 0 55 0 0 19 0 0 10 % A
% Cys: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 91 0 0 0 0 0 0 10 0 91 0 10 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 91 0 0 0 0 0 0 91 0 % G
% His: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % I
% Lys: 0 0 0 55 82 46 0 10 0 64 0 0 64 0 0 % K
% Leu: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 10 % L
% Met: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 91 0 0 0 10 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 10 0 0 37 0 28 0 19 0 10 28 0 0 % R
% Ser: 0 10 0 0 0 0 0 55 28 0 0 46 0 0 19 % S
% Thr: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 19 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _