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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT2
All Species:
31.21
Human Site:
T254
Identified Species:
68.67
UniProt:
P09544
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09544
NP_003382.1
360
40418
T254
N
Q
D
G
T
G
F
T
V
A
N
E
R
F
K
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
T254
N
Q
D
G
T
G
F
T
V
A
N
E
R
F
K
Rhesus Macaque
Macaca mulatta
XP_001107861
391
43684
T285
T
Q
D
G
A
N
F
T
A
A
R
Q
G
Y
R
Dog
Lupus familis
XP_854963
360
40149
T254
N
Q
D
G
T
G
F
T
V
A
N
K
R
F
K
Cat
Felis silvestris
Mouse
Mus musculus
P21552
360
40478
T254
N
Q
D
G
T
G
F
T
V
A
N
K
R
F
K
Rat
Rattus norvegicus
Q9QXQ7
380
42265
V285
L
N
S
R
G
K
L
V
Q
V
N
S
R
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
T255
N
Q
D
G
T
G
F
T
V
A
N
K
R
F
K
Chicken
Gallus gallus
Q98SN7
385
42934
T279
N
Q
D
G
T
G
F
T
V
A
N
K
N
F
R
Frog
Xenopus laevis
P87387
351
40101
A245
N
Q
D
G
S
G
F
A
V
A
N
Q
N
F
R
Zebra Danio
Brachydanio rerio
Q92048
350
39771
T252
N
Q
Y
G
T
G
F
T
S
A
Y
R
M
L
K
Tiger Blowfish
Takifugu rubipres
NP_001163831
350
38935
T252
N
Q
Y
G
T
G
F
T
T
A
H
A
H
F
K
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
61.3
93
N.A.
96.1
46.5
N.A.
89.7
69.6
71.6
68.3
67.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
73.6
95.2
N.A.
97.5
60.5
N.A.
93
80.5
84.1
80.8
81.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
40
93.3
N.A.
93.3
20
N.A.
93.3
80
66.6
60
66.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
60
100
N.A.
100
20
N.A.
100
93.3
86.6
60
73.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
10
91
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
73
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% E
% Phe:
0
0
0
0
0
0
91
0
0
0
0
0
0
82
0
% F
% Gly:
0
0
0
91
10
82
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
0
37
0
0
64
% K
% Leu:
10
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
82
10
0
0
0
10
0
0
0
0
73
0
19
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
91
0
0
0
0
0
0
10
0
0
19
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
10
10
55
0
28
% R
% Ser:
0
0
10
0
10
0
0
0
10
0
0
10
0
0
0
% S
% Thr:
10
0
0
0
73
0
0
82
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
64
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
19
0
0
0
0
0
0
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _