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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSF1
All Species:
9.39
Human Site:
S174
Identified Species:
41.33
UniProt:
P09603
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09603
NP_000748.3
554
60119
S174
F
S
K
N
C
N
N
S
F
A
E
C
S
S
Q
Chimpanzee
Pan troglodytes
XP_513655
443
48537
M65
Q
Q
L
I
D
S
Q
M
E
T
S
C
Q
I
T
Rhesus Macaque
Macaca mulatta
XP_001090841
445
48881
S68
I
D
S
Q
M
E
T
S
C
Q
I
T
F
E
F
Dog
Lupus familis
XP_854600
575
62028
S191
F
S
K
N
C
N
N
S
F
A
K
C
S
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
P07141
552
60630
S174
F
T
K
N
C
N
N
S
F
A
K
C
S
S
R
Rat
Rattus norvegicus
Q8JZQ0
566
62168
K185
S
S
R
D
V
V
T
K
P
D
C
N
C
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.9
74.5
70.7
N.A.
70.4
63
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
77.4
75.8
77
N.A.
79.7
74.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
93.3
N.A.
80
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
6.6
100
N.A.
100
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% A
% Cys:
0
0
0
0
50
0
0
0
17
0
17
67
17
0
0
% C
% Asp:
0
17
0
17
17
0
0
0
0
17
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
17
0
0
17
0
17
0
0
17
0
% E
% Phe:
50
0
0
0
0
0
0
0
50
0
0
0
17
0
17
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
17
0
0
0
0
0
0
17
0
0
17
0
% I
% Lys:
0
0
50
0
0
0
0
17
0
0
34
0
0
0
0
% K
% Leu:
0
0
17
0
0
0
0
0
0
0
0
0
0
17
0
% L
% Met:
0
0
0
0
17
0
0
17
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
50
0
50
50
0
0
0
0
17
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% P
% Gln:
17
17
0
17
0
0
17
0
0
17
0
0
17
0
34
% Q
% Arg:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
17
% R
% Ser:
17
50
17
0
0
17
0
67
0
0
17
0
50
50
0
% S
% Thr:
0
17
0
0
0
0
34
0
0
17
0
17
0
0
17
% T
% Val:
0
0
0
0
17
17
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _