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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDGFRB All Species: 26.67
Human Site: Y589 Identified Species: 58.67
UniProt: P09619 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09619 NP_002600.1 1106 123968 Y589 V D P M Q L P Y D S T W E L P
Chimpanzee Pan troglodytes XP_518034 1082 120774 Q589 L G S G A F G Q V V E A T A H
Rhesus Macaque Macaca mulatta XP_001107595 1106 124189 Y589 V D P M Q L P Y D S T W E L P
Dog Lupus familis XP_532374 1089 122830 Y582 V D P M Q L P Y D S R W E F P
Cat Felis silvestris
Mouse Mus musculus P05622 1098 122787 Y588 V D P V Q L P Y D S T W E L P
Rat Rattus norvegicus Q05030 1097 122809 Y588 V D P V Q L P Y D S T W E L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510424 1325 143412 K825 Q A L M S E L K I M S H L G P
Chicken Gallus gallus Q9PUF6 1087 122922 Y582 V D P M Q L P Y D S R W E F P
Frog Xenopus laevis P26619 1087 122680 Y584 V D P M Q L P Y D S R W E F P
Zebra Danio Brachydanio rerio Q9DE49 1059 118193 L574 G L V L G R V L G S G A F G K
Tiger Blowfish Takifugu rubipres P79750 975 110895 S504 A F N L V G V S S D T F T V E
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96 98.2 44.3 N.A. 85.5 85.8 N.A. 47.7 43.5 45.4 43.1 31.7 N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.3 99 62.9 N.A. 92.3 92.3 N.A. 59 60.9 63 60.2 47.6 N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 86.6 N.A. 93.3 93.3 N.A. 13.3 86.6 86.6 6.6 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 86.6 N.A. 100 100 N.A. 20 86.6 86.6 13.3 26.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 10 0 0 0 0 0 0 19 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 64 0 0 0 0 0 0 64 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 0 10 0 64 0 10 % E
% Phe: 0 10 0 0 0 10 0 0 0 0 0 10 10 28 0 % F
% Gly: 10 10 0 10 10 10 10 0 10 0 10 0 0 19 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % K
% Leu: 10 10 10 19 0 64 10 10 0 0 0 0 10 37 0 % L
% Met: 0 0 0 55 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 64 0 0 0 64 0 0 0 0 0 0 0 73 % P
% Gln: 10 0 0 0 64 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 28 0 0 0 0 % R
% Ser: 0 0 10 0 10 0 0 10 10 73 10 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 46 0 19 0 0 % T
% Val: 64 0 10 19 10 0 19 0 10 10 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 64 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 64 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _