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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLD
All Species:
49.09
Human Site:
S208
Identified Species:
77.14
UniProt:
P09622
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09622
NP_000099.2
509
54177
S208
V
S
S
T
G
A
L
S
L
K
K
V
P
E
K
Chimpanzee
Pan troglodytes
XP_001165014
509
54145
S208
V
S
S
T
G
A
L
S
L
K
K
V
P
E
K
Rhesus Macaque
Macaca mulatta
XP_001095232
509
54189
S208
V
S
S
T
G
A
L
S
L
K
K
V
P
E
K
Dog
Lupus familis
XP_855591
509
54235
S208
V
S
S
T
G
A
L
S
L
K
K
V
P
E
K
Cat
Felis silvestris
Mouse
Mus musculus
O08749
509
54254
S208
V
S
S
T
G
A
L
S
L
K
K
V
P
E
K
Rat
Rattus norvegicus
Q6P6R2
509
54020
S208
V
S
S
T
G
A
L
S
L
K
K
V
P
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509701
647
68295
S346
V
S
S
T
G
A
L
S
L
K
K
V
P
E
K
Chicken
Gallus gallus
NP_001025898
508
53957
S207
V
S
S
T
G
A
L
S
L
K
K
V
P
E
K
Frog
Xenopus laevis
NP_001080894
509
54262
S208
V
S
S
T
G
A
L
S
L
K
Q
V
P
E
K
Zebra Danio
Brachydanio rerio
NP_958914
507
53542
S206
V
S
S
T
G
A
L
S
L
K
N
V
P
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649017
504
53066
A206
S
T
G
A
L
K
L
A
K
V
P
K
H
L
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_502753
495
52615
G206
P
K
K
M
V
V
I
G
A
G
V
I
G
L
E
Sea Urchin
Strong. purpuratus
XP_782447
513
54636
S212
V
S
S
T
G
A
L
S
L
E
R
V
P
D
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M5K3
507
53970
S209
V
S
S
T
G
A
L
S
L
S
E
V
P
K
K
Baker's Yeast
Sacchar. cerevisiae
P09624
499
53992
R206
S
L
K
E
I
P
K
R
L
T
I
I
G
G
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99
98
N.A.
94.8
94.6
N.A.
70.4
89.3
85.8
82.7
N.A.
66.9
N.A.
69.1
70.3
Protein Similarity:
100
100
99.6
99
N.A.
98.6
98.4
N.A.
75.1
95.6
94.3
90.1
N.A.
79.1
N.A.
78.9
81.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
86.6
N.A.
6.6
N.A.
0
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
20
N.A.
20
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.6
54.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.9
72.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
80
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
80
0
7
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
7
0
0
0
0
0
7
7
0
0
67
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
80
0
0
7
0
7
0
0
14
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% H
% Ile:
0
0
0
0
7
0
7
0
0
0
7
14
0
0
0
% I
% Lys:
0
7
14
0
0
7
7
0
7
67
54
7
0
7
67
% K
% Leu:
0
7
0
0
7
0
87
0
87
0
0
0
0
14
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
7
0
0
0
0
7
0
0
0
0
7
0
80
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% R
% Ser:
14
80
80
0
0
0
0
80
0
7
0
0
0
0
0
% S
% Thr:
0
7
0
80
0
0
0
0
0
7
0
0
0
0
0
% T
% Val:
80
0
0
0
7
7
0
0
0
7
7
80
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _