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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLD
All Species:
26.36
Human Site:
S21
Identified Species:
41.43
UniProt:
P09622
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09622
NP_000099.2
509
54177
S21
R
G
H
F
N
R
I
S
H
G
L
Q
G
L
S
Chimpanzee
Pan troglodytes
XP_001165014
509
54145
S21
R
G
H
F
N
R
I
S
H
G
L
Q
G
L
S
Rhesus Macaque
Macaca mulatta
XP_001095232
509
54189
S21
R
G
H
F
N
R
I
S
H
G
L
Q
G
L
S
Dog
Lupus familis
XP_855591
509
54235
S21
R
G
H
F
S
R
I
S
H
G
L
Q
A
V
S
Cat
Felis silvestris
Mouse
Mus musculus
O08749
509
54254
S21
K
G
H
F
N
R
I
S
H
G
L
Q
G
V
S
Rat
Rattus norvegicus
Q6P6R2
509
54020
S21
K
G
H
F
N
R
L
S
H
G
L
Q
G
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509701
647
68295
S159
A
R
P
A
S
P
A
S
G
P
R
A
Q
A
R
Chicken
Gallus gallus
NP_001025898
508
53957
H21
R
S
H
F
D
R
V
H
H
G
L
Q
G
G
C
Frog
Xenopus laevis
NP_001080894
509
54262
P21
K
N
N
F
S
K
I
P
H
G
L
Q
R
I
S
Zebra Danio
Brachydanio rerio
NP_958914
507
53542
K21
R
G
Q
H
L
P
C
K
L
H
G
A
T
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649017
504
53066
A22
T
P
L
R
T
N
A
A
I
L
G
A
L
N
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_502753
495
52615
R22
Q
F
F
Q
V
L
A
R
N
Y
S
N
T
Q
D
Sea Urchin
Strong. purpuratus
XP_782447
513
54636
S24
V
N
H
V
H
K
L
S
R
C
S
T
S
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M5K3
507
53970
T23
R
N
L
S
N
S
P
T
D
A
L
R
F
S
F
Baker's Yeast
Sacchar. cerevisiae
P09624
499
53992
T22
S
S
T
V
R
T
L
T
I
N
K
S
H
D
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99
98
N.A.
94.8
94.6
N.A.
70.4
89.3
85.8
82.7
N.A.
66.9
N.A.
69.1
70.3
Protein Similarity:
100
100
99.6
99
N.A.
98.6
98.4
N.A.
75.1
95.6
94.3
90.1
N.A.
79.1
N.A.
78.9
81.4
P-Site Identity:
100
100
100
80
N.A.
86.6
80
N.A.
6.6
60
46.6
13.3
N.A.
0
N.A.
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
93.3
N.A.
13.3
73.3
80
20
N.A.
13.3
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.6
54.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.9
72.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
20
7
0
7
0
20
7
20
7
% A
% Cys:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
7
% C
% Asp:
0
0
0
0
7
0
0
0
7
0
0
0
0
7
7
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
7
7
54
0
0
0
0
0
0
0
0
7
0
7
% F
% Gly:
0
47
0
0
0
0
0
0
7
54
14
0
40
7
0
% G
% His:
0
0
54
7
7
0
0
7
54
7
0
0
7
0
0
% H
% Ile:
0
0
0
0
0
0
40
0
14
0
0
0
0
7
0
% I
% Lys:
20
0
0
0
0
14
0
7
0
0
7
0
0
0
0
% K
% Leu:
0
0
14
0
7
7
20
0
7
7
60
0
7
20
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
7
0
40
7
0
0
7
7
0
7
0
7
0
% N
% Pro:
0
7
7
0
0
14
7
7
0
7
0
0
0
0
0
% P
% Gln:
7
0
7
7
0
0
0
0
0
0
0
54
7
7
0
% Q
% Arg:
47
7
0
7
7
47
0
7
7
0
7
7
7
0
7
% R
% Ser:
7
14
0
7
20
7
0
54
0
0
14
7
7
7
47
% S
% Thr:
7
0
7
0
7
7
0
14
0
0
0
7
14
0
0
% T
% Val:
7
0
0
14
7
0
7
0
0
0
0
0
0
20
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _