KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLD
All Species:
22.12
Human Site:
T129
Identified Species:
34.76
UniProt:
P09622
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09622
NP_000099.2
509
54177
T129
K
M
M
E
Q
K
S
T
A
V
K
A
L
T
G
Chimpanzee
Pan troglodytes
XP_001165014
509
54145
T129
K
M
M
E
Q
K
S
T
A
V
K
A
L
T
G
Rhesus Macaque
Macaca mulatta
XP_001095232
509
54189
T129
K
M
M
E
Q
K
S
T
A
V
K
A
L
T
G
Dog
Lupus familis
XP_855591
509
54235
T129
K
M
M
E
Q
K
S
T
A
V
K
A
L
T
G
Cat
Felis silvestris
Mouse
Mus musculus
O08749
509
54254
S129
K
M
M
E
Q
K
H
S
A
V
K
A
L
T
G
Rat
Rattus norvegicus
Q6P6R2
509
54020
S129
K
M
M
E
Q
K
R
S
A
V
K
A
L
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509701
647
68295
G267
K
M
M
E
Q
K
S
G
A
V
K
A
L
T
G
Chicken
Gallus gallus
NP_001025898
508
53957
A129
M
M
E
Q
K
S
S
A
V
K
A
L
T
G
G
Frog
Xenopus laevis
NP_001080894
509
54262
G129
K
M
M
E
Q
K
S
G
A
V
K
S
L
T
S
Zebra Danio
Brachydanio rerio
NP_958914
507
53542
A129
M
M
A
Q
K
S
G
A
V
K
A
L
T
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649017
504
53066
L130
K
S
N
A
V
K
A
L
T
G
G
I
A
M
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_502753
495
52615
A130
G
I
K
Q
L
F
K
A
N
K
V
G
H
V
E
Sea Urchin
Strong. purpuratus
XP_782447
513
54636
D132
K
M
M
G
Q
K
S
D
A
V
K
G
L
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M5K3
507
53970
A131
M
L
A
Q
K
D
N
A
V
K
N
L
T
R
G
Baker's Yeast
Sacchar. cerevisiae
P09624
499
53992
N130
I
E
L
L
F
K
K
N
K
V
T
Y
Y
K
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99
98
N.A.
94.8
94.6
N.A.
70.4
89.3
85.8
82.7
N.A.
66.9
N.A.
69.1
70.3
Protein Similarity:
100
100
99.6
99
N.A.
98.6
98.4
N.A.
75.1
95.6
94.3
90.1
N.A.
79.1
N.A.
78.9
81.4
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
93.3
20
80
13.3
N.A.
13.3
N.A.
0
73.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
33.3
86.6
26.6
N.A.
20
N.A.
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.6
54.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.9
72.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
7
0
0
7
27
60
0
14
47
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% D
% Glu:
0
7
7
54
0
0
0
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
7
0
0
7
14
0
7
7
14
0
14
74
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% H
% Ile:
7
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
67
0
7
0
20
74
14
0
7
27
60
0
0
7
0
% K
% Leu:
0
7
7
7
7
0
0
7
0
0
0
20
60
0
7
% L
% Met:
20
74
60
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
7
0
0
0
7
7
7
0
7
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
27
60
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% R
% Ser:
0
7
0
0
0
14
54
14
0
0
0
7
0
0
7
% S
% Thr:
0
0
0
0
0
0
0
27
7
0
7
0
20
60
0
% T
% Val:
0
0
0
0
7
0
0
0
20
67
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _