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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLD
All Species:
55.15
Human Site:
T447
Identified Species:
86.67
UniProt:
P09622
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09622
NP_000099.2
509
54177
T447
K
I
L
G
Q
K
S
T
D
R
V
L
G
A
H
Chimpanzee
Pan troglodytes
XP_001165014
509
54145
T447
K
I
L
G
Q
K
S
T
D
R
V
L
G
A
H
Rhesus Macaque
Macaca mulatta
XP_001095232
509
54189
T447
K
I
L
G
Q
K
S
T
D
R
V
L
G
A
H
Dog
Lupus familis
XP_855591
509
54235
T447
K
I
L
G
Q
K
S
T
D
R
V
L
G
A
H
Cat
Felis silvestris
Mouse
Mus musculus
O08749
509
54254
T447
K
I
L
G
H
K
S
T
D
R
V
L
G
A
H
Rat
Rattus norvegicus
Q6P6R2
509
54020
T447
K
I
L
G
H
K
S
T
D
R
I
L
G
A
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509701
647
68295
T585
K
I
L
S
H
K
S
T
D
R
M
L
G
A
H
Chicken
Gallus gallus
NP_001025898
508
53957
T446
K
I
L
S
Q
K
S
T
D
R
M
L
G
A
H
Frog
Xenopus laevis
NP_001080894
509
54262
T447
K
I
L
S
H
K
T
T
D
R
M
L
G
A
H
Zebra Danio
Brachydanio rerio
NP_958914
507
53542
T445
K
I
L
S
H
K
D
T
D
R
M
L
G
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649017
504
53066
T442
K
V
L
A
D
Q
A
T
D
K
I
L
G
T
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_502753
495
52615
T432
K
V
L
A
D
K
Q
T
D
R
M
L
G
V
H
Sea Urchin
Strong. purpuratus
XP_782447
513
54636
T451
K
M
L
S
D
A
A
T
D
R
I
L
G
A
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M5K3
507
53970
T446
K
I
L
A
D
K
E
T
D
K
I
L
G
V
H
Baker's Yeast
Sacchar. cerevisiae
P09624
499
53992
T438
K
I
L
I
D
S
K
T
E
R
I
L
G
A
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99
98
N.A.
94.8
94.6
N.A.
70.4
89.3
85.8
82.7
N.A.
66.9
N.A.
69.1
70.3
Protein Similarity:
100
100
99.6
99
N.A.
98.6
98.4
N.A.
75.1
95.6
94.3
90.1
N.A.
79.1
N.A.
78.9
81.4
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
80
86.6
73.3
73.3
N.A.
46.6
N.A.
60
60
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
93.3
86.6
80
N.A.
80
N.A.
73.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.6
54.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.9
72.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
7
14
0
0
0
0
0
0
80
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
34
0
7
0
94
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
40
0
0
0
0
0
0
0
0
100
0
0
% G
% His:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
100
% H
% Ile:
0
80
0
7
0
0
0
0
0
0
34
0
0
0
0
% I
% Lys:
100
0
0
0
0
80
7
0
0
14
0
0
0
0
0
% K
% Leu:
0
0
100
0
0
0
0
0
0
0
0
100
0
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
34
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
34
7
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
87
0
0
0
0
0
% R
% Ser:
0
0
0
34
0
7
54
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
7
100
0
0
0
0
0
7
0
% T
% Val:
0
14
0
0
0
0
0
0
0
0
34
0
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _