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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLD
All Species:
21.52
Human Site:
Y153
Identified Species:
33.81
UniProt:
P09622
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09622
NP_000099.2
509
54177
Y153
K
V
V
H
V
N
G
Y
G
K
I
T
G
K
N
Chimpanzee
Pan troglodytes
XP_001165014
509
54145
Y153
K
V
V
H
V
N
G
Y
G
K
I
T
G
K
N
Rhesus Macaque
Macaca mulatta
XP_001095232
509
54189
Y153
K
V
I
H
V
N
G
Y
G
K
I
T
G
K
N
Dog
Lupus familis
XP_855591
509
54235
Y153
K
V
V
H
V
N
G
Y
G
K
I
T
G
K
N
Cat
Felis silvestris
Mouse
Mus musculus
O08749
509
54254
F153
K
V
V
H
V
N
G
F
G
K
I
T
G
K
N
Rat
Rattus norvegicus
Q6P6R2
509
54020
F153
K
V
V
H
V
N
G
F
G
K
I
T
G
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509701
647
68295
Y291
K
V
V
H
V
P
G
Y
G
K
I
T
G
K
N
Chicken
Gallus gallus
NP_001025898
508
53957
F152
K
V
V
H
V
S
G
F
G
R
I
T
G
K
N
Frog
Xenopus laevis
NP_001080894
509
54262
F153
K
V
V
H
V
Q
G
F
G
K
I
T
G
K
N
Zebra Danio
Brachydanio rerio
NP_958914
507
53542
G151
N
K
V
T
H
V
N
G
F
G
T
I
T
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649017
504
53066
T151
T
Q
L
T
G
F
G
T
I
V
N
P
N
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_502753
495
52615
K151
G
P
N
T
V
Q
A
K
K
N
D
G
S
V
E
Sea Urchin
Strong. purpuratus
XP_782447
513
54636
G157
V
T
R
I
Q
G
H
G
K
V
M
G
P
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M5K3
507
53970
Y154
K
V
T
Y
V
K
G
Y
G
K
F
I
S
P
N
Baker's Yeast
Sacchar. cerevisiae
P09624
499
53992
P151
E
T
K
I
R
V
T
P
V
D
G
L
E
G
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99
98
N.A.
94.8
94.6
N.A.
70.4
89.3
85.8
82.7
N.A.
66.9
N.A.
69.1
70.3
Protein Similarity:
100
100
99.6
99
N.A.
98.6
98.4
N.A.
75.1
95.6
94.3
90.1
N.A.
79.1
N.A.
78.9
81.4
P-Site Identity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
93.3
80
86.6
6.6
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
93.3
6.6
N.A.
20
N.A.
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.6
54.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.9
72.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
0
0
0
7
7
14
% E
% Phe:
0
0
0
0
0
7
0
27
7
0
7
0
0
0
0
% F
% Gly:
7
0
0
0
7
7
74
14
67
7
7
14
60
14
0
% G
% His:
0
0
0
60
7
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
14
0
0
0
0
7
0
60
14
0
0
0
% I
% Lys:
67
7
7
0
0
7
0
7
14
60
0
0
0
60
7
% K
% Leu:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
7
0
7
0
0
40
7
0
0
7
7
0
7
7
67
% N
% Pro:
0
7
0
0
0
7
0
7
0
0
0
7
7
7
0
% P
% Gln:
0
7
0
0
7
14
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
7
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
0
0
0
0
0
0
14
0
0
% S
% Thr:
7
14
7
20
0
0
7
7
0
0
7
60
7
0
7
% T
% Val:
7
67
60
0
74
14
0
0
7
14
0
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _