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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HNRNPA1 All Species: 4.55
Human Site: S269 Identified Species: 11.11
UniProt: P09651 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09651 NP_002127.1 372 38747 S269 G G S R G Y G S G G Q G Y G N
Chimpanzee Pan troglodytes XP_001168539 372 38700 S269 G G S R G Y G S G G Q G Y G N
Rhesus Macaque Macaca mulatta Q28521 320 34202 R218 G G N D N F G R G G N F S G R
Dog Lupus familis XP_543834 433 48246 R303 D Q C F A K P R N Q D G Y G G
Cat Felis silvestris
Mouse Mus musculus Q8BG05 379 39633 N276 G F G G D G G N Y G G G P G Y
Rat Rattus norvegicus A7VJC2 353 37459 G250 G Y N G Y G G G P G G G N F G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZI72 301 33425 Q199 P K E V Y R Q Q Q Q Q Q K G G
Frog Xenopus laevis P17130 365 38299 A261 G W N R G Y G A G Q G G G Y G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48810 385 39481 G270 G G W N Q Q G G S G G G P W N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22037 346 36325 P244 G P G A Y G G P G G G G Q G G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 85.2 49.8 N.A. 76.5 65.8 N.A. N.A. 31.9 77.4 N.A. N.A. 46.7 N.A. 46.5 N.A.
Protein Similarity: 100 100 85.7 55.6 N.A. 81.2 74.7 N.A. N.A. 51 81.4 N.A. N.A. 62.8 N.A. 58.5 N.A.
P-Site Identity: 100 100 40 20 N.A. 33.3 26.6 N.A. N.A. 13.3 46.6 N.A. N.A. 40 N.A. 40 N.A.
P-Site Similarity: 100 100 53.3 20 N.A. 40 33.3 N.A. N.A. 13.3 60 N.A. N.A. 40 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 10 10 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 10 0 10 0 0 0 0 0 10 0 10 0 % F
% Gly: 80 40 20 20 30 30 80 20 50 70 50 80 10 70 50 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 10 0 0 0 0 0 0 10 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 30 10 10 0 0 10 10 0 10 0 10 0 30 % N
% Pro: 10 10 0 0 0 0 10 10 10 0 0 0 20 0 0 % P
% Gln: 0 10 0 0 10 10 10 10 10 30 30 10 10 0 0 % Q
% Arg: 0 0 0 30 0 10 0 20 0 0 0 0 0 0 10 % R
% Ser: 0 0 20 0 0 0 0 20 10 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 10 10 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 10 0 0 30 30 0 0 10 0 0 0 30 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _