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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C1S
All Species:
18.18
Human Site:
Y671
Identified Species:
50
UniProt:
P09871
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09871
NP_001725.1
688
76684
Y671
L
Y
T
R
V
K
N
Y
V
D
W
I
M
K
T
Chimpanzee
Pan troglodytes
Q5R1W3
705
80186
S681
V
S
W
G
I
G
C
S
R
G
Y
G
F
Y
T
Rhesus Macaque
Macaca mulatta
XP_001111586
688
76624
Y671
L
Y
T
R
V
Q
N
Y
V
D
W
I
K
K
T
Dog
Lupus familis
XP_853320
695
77512
N677
G
I
Y
T
R
V
K
N
Y
I
D
W
I
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG14
688
76839
Y671
V
Y
T
K
V
K
N
Y
V
D
W
I
L
K
T
Rat
Rattus norvegicus
Q6P6T1
688
77053
Y671
I
Y
T
K
V
K
N
Y
V
D
W
I
L
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025948
690
77308
Y670
L
Y
T
K
V
V
R
Y
V
D
W
I
T
E
T
Frog
Xenopus laevis
NP_001089125
687
76773
N660
G
F
Y
T
K
V
D
N
Y
L
D
W
I
E
K
Zebra Danio
Brachydanio rerio
NP_001116330
684
76146
K668
G
Y
Y
G
V
Y
T
K
V
S
N
Y
L
S
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.2
93.9
78.9
N.A.
74.1
76.1
N.A.
N.A.
55.5
51.3
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
55.5
96.3
87.9
N.A.
85
86.4
N.A.
N.A.
72.1
67.4
56.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
86.6
0
N.A.
80
80
N.A.
N.A.
66.6
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
93.3
13.3
N.A.
100
100
N.A.
N.A.
80
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
56
23
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
34
0
0
23
0
12
0
0
0
12
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
12
0
0
12
0
0
0
0
12
0
56
23
0
0
% I
% Lys:
0
0
0
34
12
34
12
12
0
0
0
0
12
45
12
% K
% Leu:
34
0
0
0
0
0
0
0
0
12
0
0
34
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
45
23
0
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
12
% Q
% Arg:
0
0
0
23
12
0
12
0
12
0
0
0
0
12
0
% R
% Ser:
0
12
0
0
0
0
0
12
0
12
0
0
0
12
0
% S
% Thr:
0
0
56
23
0
0
12
0
0
0
0
0
12
0
67
% T
% Val:
23
0
0
0
67
34
0
0
67
0
0
0
0
0
0
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
56
23
0
0
12
% W
% Tyr:
0
67
34
0
0
12
0
56
23
0
12
12
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _