Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLA1 All Species: 33.33
Human Site: S458 Identified Species: 66.67
UniProt: P09884 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09884 NP_058633.2 1462 165913 S458 E Y L E V K Y S A E M P Q L P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001091195 1462 165768 S458 E Y L E V K Y S A E I P Q L P
Dog Lupus familis XP_537985 1590 179675 S464 E Y L E V R Y S A E M P Q L P
Cat Felis silvestris
Mouse Mus musculus P33609 1465 167321 S462 E Y L E V R Y S A E V P Q L P
Rat Rattus norvegicus O89042 1451 165288 S465 E Y L E V R Y S A E V P Q L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416792 1496 170879 S482 E Y L E V K Y S A E Y P R L P
Frog Xenopus laevis Q9DE46 1458 165042 S458 E Y L E V R Y S A D S P Q L P
Zebra Danio Brachydanio rerio XP_001922054 1470 166510 S468 E Y L E V K Y S A E I P S L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26019 1488 169885 H474 S C D Y L E V H Y D G K K P L
Honey Bee Apis mellifera XP_001121438 1239 142457 A335 Y L E V R Y A A H Y P P M P S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FHA3 1492 167126 S477 Y V L K I N Y S F K D R P L P
Baker's Yeast Sacchar. cerevisiae P13382 1468 166791 P451 D Y L K V L L P Y Q T P K S S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.7 84.4 N.A. 88 89 N.A. N.A. 73.8 72.5 68.9 N.A. 40 39.4 N.A. N.A.
Protein Similarity: 100 N.A. 99 87.9 N.A. 92.4 93 N.A. N.A. 84.8 84.1 82.1 N.A. 58.7 56.1 N.A. N.A.
P-Site Identity: 100 N.A. 93.3 93.3 N.A. 86.6 86.6 N.A. N.A. 86.6 80 86.6 N.A. 0 6.6 N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 93.3 93.3 93.3 N.A. 26.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.8 32.2 N.A.
Protein Similarity: N.A. N.A. N.A. 54.8 52.2 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 9 67 0 0 0 0 0 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 0 0 0 0 0 0 17 9 0 0 0 0 % D
% Glu: 67 0 9 67 0 9 0 0 0 59 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 17 0 0 0 0 % I
% Lys: 0 0 0 17 0 34 0 0 0 9 0 9 17 0 0 % K
% Leu: 0 9 84 0 9 9 9 0 0 0 0 0 0 75 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 17 0 9 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 9 0 0 9 84 9 17 75 % P
% Gln: 0 0 0 0 0 0 0 0 0 9 0 0 50 0 0 % Q
% Arg: 0 0 0 0 9 34 0 0 0 0 0 9 9 0 0 % R
% Ser: 9 0 0 0 0 0 0 75 0 0 9 0 9 9 17 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % T
% Val: 0 9 0 9 75 0 9 0 0 0 17 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 17 75 0 9 0 9 75 0 17 9 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _