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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLA1
All Species:
27.88
Human Site:
Y414
Identified Species:
55.76
UniProt:
P09884
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09884
NP_058633.2
1462
165913
Y414
P
I
S
M
K
D
V
Y
E
E
F
D
E
K
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001091195
1462
165768
Y414
P
V
S
M
K
D
V
Y
E
E
F
D
E
K
I
Dog
Lupus familis
XP_537985
1590
179675
Y420
L
V
T
M
K
D
V
Y
D
E
F
D
E
K
I
Cat
Felis silvestris
Mouse
Mus musculus
P33609
1465
167321
Y418
P
V
T
M
K
D
V
Y
E
E
F
D
S
K
I
Rat
Rattus norvegicus
O89042
1451
165288
Y421
P
I
T
M
K
D
V
Y
E
E
F
D
S
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416792
1496
170879
F438
P
V
T
I
M
N
V
F
K
E
F
N
D
C
I
Frog
Xenopus laevis
Q9DE46
1458
165042
Y414
P
V
S
M
M
H
V
Y
Q
E
F
N
E
A
V
Zebra Danio
Brachydanio rerio
XP_001922054
1470
166510
V424
V
A
V
G
M
M
D
V
Y
K
E
F
N
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26019
1488
169885
Y430
K
V
T
V
A
D
I
Y
K
E
F
D
S
E
V
Honey Bee
Apis mellifera
XP_001121438
1239
142457
Y291
L
N
T
M
E
D
V
Y
K
E
F
N
Q
F
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FHA3
1492
167126
K433
H
E
M
A
S
K
L
K
N
E
I
A
Q
E
L
Baker's Yeast
Sacchar. cerevisiae
P13382
1468
166791
H407
G
K
T
P
T
D
I
H
E
E
I
I
P
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.7
84.4
N.A.
88
89
N.A.
N.A.
73.8
72.5
68.9
N.A.
40
39.4
N.A.
N.A.
Protein Similarity:
100
N.A.
99
87.9
N.A.
92.4
93
N.A.
N.A.
84.8
84.1
82.1
N.A.
58.7
56.1
N.A.
N.A.
P-Site Identity:
100
N.A.
93.3
73.3
N.A.
80
86.6
N.A.
N.A.
33.3
53.3
6.6
N.A.
33.3
40
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
80
20
N.A.
80
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.8
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.8
52.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
9
0
0
0
0
0
0
9
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
67
9
0
9
0
0
50
9
0
0
% D
% Glu:
0
9
0
0
9
0
0
0
42
92
9
0
34
25
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
75
9
0
9
0
% F
% Gly:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
17
0
9
0
0
17
0
0
0
17
9
0
0
59
% I
% Lys:
9
9
0
0
42
9
0
9
25
9
0
0
0
42
0
% K
% Leu:
17
0
0
0
0
0
9
0
0
0
0
0
0
9
17
% L
% Met:
0
0
9
59
25
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
9
0
0
9
0
0
25
9
0
0
% N
% Pro:
50
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
17
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
25
0
9
0
0
0
0
0
0
0
25
0
0
% S
% Thr:
0
0
59
0
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
50
9
9
0
0
67
9
0
0
0
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _