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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALOX5 All Species: 25.15
Human Site: S462 Identified Species: 61.48
UniProt: P09917 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09917 NP_000689.1 674 77983 S462 I K A R G M E S K E D I P Y Y
Chimpanzee Pan troglodytes XP_507763 906 101718 S599 I K A R G M E S K E D I P Y Y
Rhesus Macaque Macaca mulatta XP_001102354 674 77863 S462 I K A R G M E S K E D I P Y Y
Dog Lupus familis XP_534950 690 79170 S478 I K A R G M D S T E D I P Y Y
Cat Felis silvestris
Mouse Mus musculus P48999 674 77981 S462 I K A R G M D S T E D M P F Y
Rat Rattus norvegicus P12527 673 78069 N461 I K A R G M D N T E D I P Y Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423676 651 74206 G439 P E D I Q A R G V S F I P N Y
Frog Xenopus laevis NP_001089265 670 75862 S461 I Q A R G V D S V P N Y F Y R
Zebra Danio Brachydanio rerio XP_695587 674 78343 S462 I K A R G M D S Q E E L P Y Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LUW0 886 101041 V644 D P N S D N G V K L L I E D Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.1 98 86 N.A. 93.1 92.8 N.A. N.A. 44.6 41.3 74.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 71.4 98.9 91.3 N.A. 97.1 96.8 N.A. N.A. 62 62.4 88.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 73.3 80 N.A. N.A. 20 40 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 26.6 66.6 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 80 0 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 10 0 50 0 0 0 60 0 0 10 0 % D
% Glu: 0 10 0 0 0 0 30 0 0 70 10 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 10 10 0 % F
% Gly: 0 0 0 0 80 0 10 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 80 0 0 10 0 0 0 0 0 0 0 70 0 0 0 % I
% Lys: 0 70 0 0 0 0 0 0 40 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 10 10 10 0 0 0 % L
% Met: 0 0 0 0 0 70 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 10 0 0 10 0 10 0 0 10 0 0 10 0 % N
% Pro: 10 10 0 0 0 0 0 0 0 10 0 0 80 0 0 % P
% Gln: 0 10 0 0 10 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 0 0 80 0 0 10 0 0 0 0 0 0 0 10 % R
% Ser: 0 0 0 10 0 0 0 70 0 10 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 30 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 10 0 10 20 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 70 90 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _