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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPI
All Species:
12.73
Human Site:
S196
Identified Species:
23.33
UniProt:
P09923
Number Species:
12
Phosphosite Substitution
Charge Score:
0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09923
NP_001622.2
528
56812
S196
S
D
A
D
M
P
A
S
A
R
Q
E
G
C
Q
Chimpanzee
Pan troglodytes
XP_001142681
961
103936
S629
S
D
A
D
M
P
A
S
A
R
Q
D
G
C
Q
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
E323
S
D
N
E
M
P
P
E
A
L
S
Q
G
C
K
Dog
Lupus familis
XP_534605
554
59751
K199
S
D
A
N
M
P
A
K
A
L
E
D
G
C
Q
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
S195
S
D
A
Q
M
P
A
S
A
L
Q
D
G
C
K
Rat
Rattus norvegicus
P15693
540
58384
S197
S
D
A
D
M
P
S
S
A
L
Q
E
G
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
D194
S
D
G
E
M
P
L
D
A
L
E
G
G
C
K
Frog
Xenopus laevis
NP_001091135
530
58155
N199
S
D
G
D
M
P
A
N
A
V
E
A
G
C
K
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
E200
S
D
K
E
L
T
S
E
A
V
A
G
G
C
Q
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
E199
S
D
S
V
M
P
A
E
A
V
Q
D
G
C
K
Fruit Fly
Dros. melanogaster
Q24238
596
65244
E226
C
D
T
E
V
P
A
E
S
V
G
F
H
V
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
E195
S
D
N
E
M
P
P
E
A
L
S
Q
G
C
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
V184
P
A
S
F
S
S
H
V
D
Y
R
W
Q
E
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.1
47.7
76.3
N.A.
75.8
76.1
N.A.
N.A.
57.3
63.9
59.4
56.2
41.1
N.A.
N.A.
N.A.
Protein Similarity:
100
54.5
59.5
83
N.A.
85.6
85.5
N.A.
N.A.
71.5
76.7
73.1
71.5
54
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
46.6
66.6
N.A.
73.3
80
N.A.
N.A.
46.6
60
40
60
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
66.6
86.6
N.A.
86.6
93.3
N.A.
N.A.
66.6
80
60
80
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
57
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
73.1
N.A.
N.A.
41.3
N.A.
P-Site Identity:
N.A.
46.6
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
39
0
0
0
54
0
85
0
8
8
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
85
0
% C
% Asp:
0
93
0
31
0
0
0
8
8
0
0
31
0
0
16
% D
% Glu:
0
0
0
39
0
0
0
39
0
0
24
16
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
16
0
0
0
0
0
0
0
8
16
85
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
54
% K
% Leu:
0
0
0
0
8
0
8
0
0
47
0
0
0
0
0
% L
% Met:
0
0
0
0
77
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
16
8
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
85
16
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
39
16
8
0
31
% Q
% Arg:
0
0
0
0
0
0
0
0
0
16
8
0
0
0
0
% R
% Ser:
85
0
16
0
8
8
16
31
8
0
16
0
0
0
0
% S
% Thr:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
0
8
0
31
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _