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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPI
All Species:
4.24
Human Site:
S241
Identified Species:
7.78
UniProt:
P09923
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09923
NP_001622.2
528
56812
S241
P
E
Y
P
A
D
A
S
Q
N
G
I
R
L
D
Chimpanzee
Pan troglodytes
XP_001142681
961
103936
S674
P
E
Y
P
G
D
A
S
Q
N
G
I
R
L
D
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
E368
D
V
E
Y
E
I
D
E
K
A
R
G
T
R
L
Dog
Lupus familis
XP_534605
554
59751
K244
P
E
Y
P
T
D
A
K
Q
N
G
I
R
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
K240
Q
E
Y
P
T
D
T
K
Q
A
G
T
R
L
D
Rat
Rattus norvegicus
P15693
540
58384
D242
P
E
Y
P
G
D
S
D
Q
S
G
V
R
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
E239
D
V
E
Y
P
Q
E
E
R
H
R
G
T
R
L
Frog
Xenopus laevis
NP_001091135
530
58155
K244
P
E
Y
P
A
D
S
K
Q
N
G
I
R
K
D
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
G245
P
E
Y
S
T
V
T
G
S
R
K
D
K
R
N
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
A244
D
V
E
Y
P
D
T
A
K
Y
S
G
I
R
K
Fruit Fly
Dros. melanogaster
Q24238
596
65244
F271
S
E
V
K
T
T
I
F
E
G
P
T
E
T
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
E240
D
V
E
Y
E
L
D
E
K
A
R
G
T
R
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
G229
G
E
K
A
S
P
Y
G
H
H
G
A
R
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.1
47.7
76.3
N.A.
75.8
76.1
N.A.
N.A.
57.3
63.9
59.4
56.2
41.1
N.A.
N.A.
N.A.
Protein Similarity:
100
54.5
59.5
83
N.A.
85.6
85.5
N.A.
N.A.
71.5
76.7
73.1
71.5
54
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
0
86.6
N.A.
60
66.6
N.A.
N.A.
0
80
20
6.6
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
6.6
86.6
N.A.
60
86.6
N.A.
N.A.
13.3
86.6
33.3
20
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
57
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
73.1
N.A.
N.A.
41.3
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
16
0
24
8
0
24
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
31
0
0
0
0
54
16
8
0
0
0
8
0
0
54
% D
% Glu:
0
70
31
0
16
0
8
24
8
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
16
0
0
16
0
8
54
31
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
16
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
0
0
0
31
8
0
8
% I
% Lys:
0
0
8
8
0
0
0
24
24
0
8
0
8
16
8
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
0
0
0
39
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
8
% N
% Pro:
47
0
0
47
16
8
0
0
0
0
8
0
0
0
0
% P
% Gln:
8
0
0
0
0
8
0
0
47
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
8
24
0
54
39
0
% R
% Ser:
8
0
0
8
8
0
16
16
8
8
8
0
0
0
0
% S
% Thr:
0
0
0
0
31
8
24
0
0
0
0
16
24
8
0
% T
% Val:
0
31
8
0
0
8
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
54
31
0
0
8
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _