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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPI
All Species:
10.3
Human Site:
S399
Identified Species:
18.89
UniProt:
P09923
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09923
NP_001622.2
528
56812
S399
S
I
F
G
L
A
P
S
K
A
Q
D
S
K
A
Chimpanzee
Pan troglodytes
XP_001142681
961
103936
S832
S
I
F
G
L
A
P
S
K
A
Q
D
S
K
A
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
M529
S
I
F
G
L
A
P
M
L
S
D
T
D
K
K
Dog
Lupus familis
XP_534605
554
59751
S402
S
I
F
G
L
A
P
S
M
A
K
D
N
K
T
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
F398
S
I
F
G
L
A
P
F
K
A
E
D
G
K
S
Rat
Rattus norvegicus
P15693
540
58384
L400
S
I
F
G
L
A
P
L
N
A
Q
D
G
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
M400
P
I
F
G
L
A
P
M
Q
S
D
V
D
R
K
Frog
Xenopus laevis
NP_001091135
530
58155
K401
S
I
F
G
L
A
P
K
K
A
F
D
N
K
Y
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
A399
P
V
L
G
V
S
Y
A
K
G
E
D
G
K
S
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
A404
T
I
F
G
L
A
P
A
V
S
D
V
D
Q
K
Fruit Fly
Dros. melanogaster
Q24238
596
65244
S438
D
I
L
G
T
A
N
S
H
E
K
N
D
P
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
M401
S
I
F
G
L
A
P
M
V
S
D
T
D
K
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
G406
L
A
N
A
T
H
S
G
E
F
L
K
R
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.1
47.7
76.3
N.A.
75.8
76.1
N.A.
N.A.
57.3
63.9
59.4
56.2
41.1
N.A.
N.A.
N.A.
Protein Similarity:
100
54.5
59.5
83
N.A.
85.6
85.5
N.A.
N.A.
71.5
76.7
73.1
71.5
54
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
73.3
N.A.
73.3
73.3
N.A.
N.A.
40
73.3
26.6
40
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
60
86.6
N.A.
86.6
80
N.A.
N.A.
60
80
66.6
66.6
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
57
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
73.1
N.A.
N.A.
41.3
N.A.
P-Site Identity:
N.A.
53.3
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
60
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
85
0
16
0
47
0
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
31
54
39
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
8
16
0
0
0
0
% E
% Phe:
0
0
77
0
0
0
0
8
0
8
8
0
0
0
0
% F
% Gly:
0
0
0
93
0
0
0
8
0
8
0
0
24
0
0
% G
% His:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
85
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
39
0
16
8
0
77
31
% K
% Leu:
8
0
16
0
77
0
0
8
8
0
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
24
8
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
8
0
8
0
0
8
16
0
0
% N
% Pro:
16
0
0
0
0
0
77
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
24
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% R
% Ser:
62
0
0
0
0
8
8
31
0
31
0
0
16
0
24
% S
% Thr:
8
0
0
0
16
0
0
0
0
0
0
16
0
0
8
% T
% Val:
0
8
0
0
8
0
0
0
16
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _