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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALPI All Species: 30.61
Human Site: T86 Identified Species: 56.11
UniProt: P09923 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09923 NP_001622.2 528 56812 T86 N G K L G P E T P L A M D R F
Chimpanzee Pan troglodytes XP_001142681 961 103936 T519 N G K L G P E T P L A M D R F
Rhesus Macaque Macaca mulatta XP_001109717 652 71041 T213 H H N P G E E T R L E M D K F
Dog Lupus familis XP_534605 554 59751 T89 N D N L G P E T P L A M D Q F
Cat Felis silvestris
Mouse Mus musculus P24823 529 57193 T85 Q G L S G P E T Q L A M D R F
Rat Rattus norvegicus P15693 540 58384 T87 G G H L G P E T P L A M D H F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q92058 519 56742 S84 Q H R K G E E S L L E M D K F
Frog Xenopus laevis NP_001091135 530 58155 N89 K S M L G E E N E L A M D K F
Zebra Danio Brachydanio rerio NP_001020359 521 56944 S90 N K K T G E E S V L A M D T F
Tiger Blowfish Takifugu rubipres NP_001027823 527 57490 T89 S G Q S G E E T Q L E M D K F
Fruit Fly Dros. melanogaster Q24238 596 65244 G116 Q Y L K H G Y G E E E T L V F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001130844 524 57641 T85 H H N T G E E T R L E M D K F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P11491 566 62986 T74 K N V I F F V T D G M G P A S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.1 47.7 76.3 N.A. 75.8 76.1 N.A. N.A. 57.3 63.9 59.4 56.2 41.1 N.A. N.A. N.A.
Protein Similarity: 100 54.5 59.5 83 N.A. 85.6 85.5 N.A. N.A. 71.5 76.7 73.1 71.5 54 N.A. N.A. N.A.
P-Site Identity: 100 100 46.6 80 N.A. 73.3 80 N.A. N.A. 40 53.3 60 53.3 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 60 86.6 N.A. 73.3 80 N.A. N.A. 60 60 66.6 73.3 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 57 N.A. N.A. 25.6 N.A.
Protein Similarity: N.A. 73.1 N.A. N.A. 41.3 N.A.
P-Site Identity: N.A. 46.6 N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. 60 N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 54 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 8 0 0 0 85 0 0 % D
% Glu: 0 0 0 0 0 47 85 0 16 8 39 0 0 0 0 % E
% Phe: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 93 % F
% Gly: 8 39 0 0 85 8 0 8 0 8 0 8 0 0 0 % G
% His: 16 24 8 0 8 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 16 8 24 16 0 0 0 0 0 0 0 0 0 39 0 % K
% Leu: 0 0 16 39 0 0 0 0 8 85 0 0 8 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 8 85 0 0 0 % M
% Asn: 31 8 24 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 39 0 0 31 0 0 0 8 0 0 % P
% Gln: 24 0 8 0 0 0 0 0 16 0 0 0 0 8 0 % Q
% Arg: 0 0 8 0 0 0 0 0 16 0 0 0 0 24 0 % R
% Ser: 8 8 0 16 0 0 0 16 0 0 0 0 0 0 8 % S
% Thr: 0 0 0 16 0 0 0 70 0 0 0 8 0 8 0 % T
% Val: 0 0 8 0 0 0 8 0 8 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _