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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPI
All Species:
25.45
Human Site:
Y326
Identified Species:
46.67
UniProt:
P09923
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09923
NP_001622.2
528
56812
Y326
S
R
N
P
R
G
F
Y
L
F
V
E
G
G
R
Chimpanzee
Pan troglodytes
XP_001142681
961
103936
F759
S
R
N
P
R
G
F
F
L
F
V
E
G
G
R
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
F456
R
K
N
P
K
G
F
F
L
L
V
E
G
G
R
Dog
Lupus familis
XP_534605
554
59751
Y329
S
R
N
P
K
G
F
Y
L
F
V
E
G
G
R
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
Y325
S
R
N
P
K
G
F
Y
L
F
V
E
G
G
R
Rat
Rattus norvegicus
P15693
540
58384
Y327
S
R
N
P
Q
G
F
Y
L
F
V
E
G
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
F327
Q
K
N
P
R
G
F
F
L
L
V
E
G
G
R
Frog
Xenopus laevis
NP_001091135
530
58155
Y328
Q
R
N
P
K
G
F
Y
L
F
V
E
G
G
R
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
Y326
R
K
N
P
N
G
F
Y
L
F
V
E
G
G
R
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
Y331
K
K
N
P
N
G
F
Y
L
L
V
E
G
G
R
Fruit Fly
Dros. melanogaster
Q24238
596
65244
F364
R
G
D
E
S
N
G
F
V
L
L
V
E
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
F328
T
K
N
P
K
G
F
F
L
L
V
E
G
G
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
K315
E
K
A
S
N
E
D
K
D
S
N
G
F
F
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.1
47.7
76.3
N.A.
75.8
76.1
N.A.
N.A.
57.3
63.9
59.4
56.2
41.1
N.A.
N.A.
N.A.
Protein Similarity:
100
54.5
59.5
83
N.A.
85.6
85.5
N.A.
N.A.
71.5
76.7
73.1
71.5
54
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
66.6
93.3
N.A.
93.3
93.3
N.A.
N.A.
73.3
86.6
80
73.3
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
N.A.
86.6
93.3
86.6
80
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
57
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
73.1
N.A.
N.A.
41.3
N.A.
P-Site Identity:
N.A.
66.6
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
8
0
8
0
0
0
0
0
0
% D
% Glu:
8
0
0
8
0
8
0
0
0
0
0
85
8
0
0
% E
% Phe:
0
0
0
0
0
0
85
39
0
54
0
0
8
8
0
% F
% Gly:
0
8
0
0
0
85
8
0
0
0
0
8
85
93
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
47
0
0
39
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
85
39
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
85
0
24
8
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
85
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
16
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
24
47
0
0
24
0
0
0
0
0
0
0
0
0
85
% R
% Ser:
39
0
0
8
8
0
0
0
0
8
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
85
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _