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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALPI
All Species:
22.42
Human Site:
Y438
Identified Species:
41.11
UniProt:
P09923
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09923
NP_001622.2
528
56812
Y438
S
E
S
G
S
P
D
Y
Q
Q
Q
A
A
V
P
Chimpanzee
Pan troglodytes
XP_001142681
961
103936
Y871
S
E
S
G
D
P
D
Y
Q
Q
Q
A
A
V
P
Rhesus Macaque
Macaca mulatta
XP_001109717
652
71041
N568
M
V
D
Y
A
H
N
N
Y
Q
A
Q
S
A
V
Dog
Lupus familis
XP_534605
554
59751
Y441
A
E
S
R
D
P
A
Y
K
P
Q
A
A
V
P
Cat
Felis silvestris
Mouse
Mus musculus
P24823
529
57193
Y437
E
E
S
S
N
P
T
Y
Q
Q
Q
A
C
V
P
Rat
Rattus norvegicus
P15693
540
58384
Y439
A
E
S
G
D
V
N
Y
K
Q
Q
A
A
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92058
519
56742
N439
A
V
D
F
A
H
A
N
Y
Q
A
Q
A
A
V
Frog
Xenopus laevis
NP_001091135
530
58155
Y440
N
L
S
E
D
V
N
Y
M
Q
Q
A
A
V
P
Zebra Danio
Brachydanio rerio
NP_001020359
521
56944
Y438
S
V
S
G
R
D
D
Y
L
Q
Q
A
A
V
P
Tiger Blowfish
Takifugu rubipres
NP_001027823
527
57490
N443
A
I
D
Y
Q
E
N
N
Y
Q
A
Q
A
A
V
Fruit Fly
Dros. melanogaster
Q24238
596
65244
P477
N
S
S
N
M
W
M
P
L
K
H
F
T
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130844
524
57641
N440
M
V
D
Y
A
H
N
N
Y
Q
A
Q
S
A
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11491
566
62986
Y445
K
D
L
G
I
Y
D
Y
T
D
S
D
L
E
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.1
47.7
76.3
N.A.
75.8
76.1
N.A.
N.A.
57.3
63.9
59.4
56.2
41.1
N.A.
N.A.
N.A.
Protein Similarity:
100
54.5
59.5
83
N.A.
85.6
85.5
N.A.
N.A.
71.5
76.7
73.1
71.5
54
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
60
N.A.
66.6
66.6
N.A.
N.A.
13.3
53.3
73.3
13.3
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
26.6
73.3
N.A.
73.3
86.6
N.A.
N.A.
26.6
66.6
73.3
26.6
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
57
N.A.
N.A.
25.6
N.A.
Protein Similarity:
N.A.
73.1
N.A.
N.A.
41.3
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
0
0
24
0
16
0
0
0
31
54
62
39
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
31
0
31
8
31
0
0
8
0
8
0
0
0
% D
% Glu:
8
39
0
8
0
8
0
0
0
0
0
0
0
8
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
39
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
24
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
16
8
0
0
0
0
0
% K
% Leu:
0
8
8
0
0
0
0
0
16
0
0
0
8
0
0
% L
% Met:
16
0
0
0
8
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
16
0
0
8
8
0
39
31
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
31
0
8
0
8
0
0
0
0
54
% P
% Gln:
0
0
0
0
8
0
0
0
24
77
54
31
0
0
0
% Q
% Arg:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
24
8
62
8
8
0
0
0
0
0
8
0
16
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
8
0
0
0
8
0
8
% T
% Val:
0
31
0
0
0
16
0
0
0
0
0
0
0
54
31
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
24
0
8
0
62
31
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _