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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UCHL1
All Species:
33.64
Human Site:
S125
Identified Species:
74
UniProt:
P09936
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09936
NP_004172.2
223
24824
S125
L
S
E
T
E
K
M
S
P
E
D
R
A
K
C
Chimpanzee
Pan troglodytes
XP_001147751
219
24319
S121
L
S
E
T
E
K
M
S
P
E
D
R
A
K
C
Rhesus Macaque
Macaca mulatta
XP_001097839
212
23436
S114
L
S
E
T
E
K
M
S
P
E
D
R
A
K
C
Dog
Lupus familis
XP_536245
326
34866
S228
L
S
E
T
E
K
L
S
P
E
D
R
A
K
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0P9
223
24820
S125
L
S
E
T
E
K
L
S
P
E
D
R
A
K
C
Rat
Rattus norvegicus
Q91Y78
230
26105
S130
L
E
E
S
V
A
M
S
P
E
E
R
A
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001073681
224
25092
S125
L
D
E
T
A
D
L
S
P
E
E
R
A
K
R
Frog
Xenopus laevis
NP_001090126
223
24839
S125
I
E
Q
T
A
A
L
S
P
E
E
R
A
I
H
Zebra Danio
Brachydanio rerio
NP_958885
218
24230
S120
L
E
A
T
S
G
M
S
P
A
E
R
A
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35122
227
25832
S126
L
E
K
T
A
S
L
S
P
E
E
R
G
R
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35127
236
26367
V146
L
N
V
I
K
E
N
V
Q
T
F
S
T
G
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
94.1
63.1
N.A.
95.5
54.7
N.A.
N.A.
75
70.8
66.8
N.A.
45.3
N.A.
N.A.
N.A.
Protein Similarity:
100
98.2
94.6
66.8
N.A.
99
74.7
N.A.
N.A.
87.9
83.4
79.8
N.A.
66
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
53.3
N.A.
N.A.
60
40
53.3
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
73.3
N.A.
N.A.
73.3
66.6
60
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
28
19
0
0
0
10
0
0
82
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
46
% C
% Asp:
0
10
0
0
0
10
0
0
0
0
46
0
0
0
0
% D
% Glu:
0
37
64
0
46
10
0
0
0
82
46
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% H
% Ile:
10
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
10
0
10
46
0
0
0
0
0
0
0
64
0
% K
% Leu:
91
0
0
0
0
0
46
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
46
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
91
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
91
0
19
10
% R
% Ser:
0
46
0
10
10
10
0
91
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
82
0
0
0
0
0
10
0
0
10
0
0
% T
% Val:
0
0
10
0
10
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _