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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UCHL1 All Species: 38.18
Human Site: Y173 Identified Species: 84
UniProt: P09936 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09936 NP_004172.2 223 24824 Y173 N N V D G H L Y E L D G R M P
Chimpanzee Pan troglodytes XP_001147751 219 24319 Y169 N N V D G H L Y E L D G R M P
Rhesus Macaque Macaca mulatta XP_001097839 212 23436 Y162 N N V D G H L Y E L D G R M P
Dog Lupus familis XP_536245 326 34866 Y276 N N V D G H L Y E L D G R M P
Cat Felis silvestris
Mouse Mus musculus Q9R0P9 223 24820 Y173 N N V D G H L Y E L D G R M P
Rat Rattus norvegicus Q91Y78 230 26105 Y181 V H V D G H L Y E L D G R K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001073681 224 25092 Y174 A N V D G H L Y E L D G R L P
Frog Xenopus laevis NP_001090126 223 24839 Y173 T A V D G H L Y E L D G R L P
Zebra Danio Brachydanio rerio NP_958885 218 24230 Y169 V N V D G R L Y E L D G R I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P35122 227 25832 Y176 V N K E G T L Y E L D G R K S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35127 236 26367 Y170 T N L H Y I T Y V E E N G G I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 94.1 63.1 N.A. 95.5 54.7 N.A. N.A. 75 70.8 66.8 N.A. 45.3 N.A. N.A. N.A.
Protein Similarity: 100 98.2 94.6 66.8 N.A. 99 74.7 N.A. N.A. 87.9 83.4 79.8 N.A. 66 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 80 N.A. N.A. 86.6 80 73.3 N.A. 60 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 86.6 N.A. N.A. 93.3 86.6 80 N.A. 66.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 82 0 0 0 0 0 0 91 0 0 0 10 % D
% Glu: 0 0 0 10 0 0 0 0 91 10 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 91 0 0 0 0 0 0 91 10 10 0 % G
% His: 0 10 0 10 0 73 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 10 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 0 0 19 0 % K
% Leu: 0 0 10 0 0 0 91 0 0 91 0 0 0 19 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 46 0 % M
% Asn: 46 82 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 0 91 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % S
% Thr: 19 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % T
% Val: 28 0 82 0 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _