KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FURIN
All Species:
18.18
Human Site:
S47
Identified Species:
33.33
UniProt:
P09958
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09958
NP_002560.1
794
86678
S47
G
G
P
A
V
A
N
S
V
A
R
K
H
G
F
Chimpanzee
Pan troglodytes
XP_510596
794
86649
S47
G
G
P
A
V
A
N
S
V
A
R
K
H
G
F
Rhesus Macaque
Macaca mulatta
XP_001094068
794
86687
S47
G
G
P
A
V
A
N
S
V
A
R
K
H
G
F
Dog
Lupus familis
XP_850069
801
87503
S47
G
G
P
A
V
A
D
S
L
A
R
K
H
G
F
Cat
Felis silvestris
Mouse
Mus musculus
P23188
793
86786
R47
G
G
P
A
V
A
D
R
V
A
Q
K
H
G
F
Rat
Rattus norvegicus
P23377
793
86635
S47
G
G
P
A
V
A
D
S
V
A
R
K
H
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990046
789
86613
R48
A
G
P
L
E
A
N
R
L
A
R
K
H
G
F
Frog
Xenopus laevis
P29119
783
86425
R45
G
G
S
A
E
A
D
R
L
C
K
K
Y
G
F
Zebra Danio
Brachydanio rerio
NP_001038574
823
89738
R48
G
G
V
E
E
A
E
R
I
A
Q
K
H
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26016
1269
138609
A180
P
P
P
P
P
S
S
A
L
K
V
D
P
N
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
E52
R
L
A
K
R
D
D
E
L
A
R
R
I
A
A
Sea Urchin
Strong. purpuratus
XP_780373
746
81468
Y30
S
S
E
N
G
G
V
Y
T
N
T
Y
A
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
L48
S
N
E
T
L
S
R
L
E
E
M
H
P
N
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.8
93.5
N.A.
93.6
93.6
N.A.
N.A.
79.8
70.2
63.7
N.A.
32.5
N.A.
37.4
48.9
Protein Similarity:
100
99.7
99.2
95
N.A.
95.7
95.2
N.A.
N.A.
86.4
80.8
75
N.A.
42.7
N.A.
50.2
61.2
P-Site Identity:
100
100
100
86.6
N.A.
80
93.3
N.A.
N.A.
66.6
46.6
53.3
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
73.3
73.3
66.6
N.A.
33.3
N.A.
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
54
0
70
0
8
0
70
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
39
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
16
8
24
0
8
8
8
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% F
% Gly:
62
70
0
0
8
8
0
0
0
0
0
0
0
70
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
62
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
8
8
70
0
0
0
% K
% Leu:
0
8
0
8
8
0
0
8
39
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
31
0
0
8
0
0
0
16
0
% N
% Pro:
8
8
62
8
8
0
0
0
0
0
0
0
16
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% Q
% Arg:
8
0
0
0
8
0
8
31
0
0
54
8
0
0
0
% R
% Ser:
16
8
8
0
0
16
8
39
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
8
0
8
0
0
0
0
% T
% Val:
0
0
8
0
47
0
8
0
39
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _