KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FURIN
All Species:
23.64
Human Site:
S585
Identified Species:
43.33
UniProt:
P09958
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09958
NP_002560.1
794
86678
S585
L
P
V
P
P
E
S
S
G
C
K
T
L
T
S
Chimpanzee
Pan troglodytes
XP_510596
794
86649
S585
L
P
V
P
P
E
S
S
G
C
K
T
L
T
S
Rhesus Macaque
Macaca mulatta
XP_001094068
794
86687
S585
L
P
I
P
P
E
S
S
G
C
K
T
L
T
S
Dog
Lupus familis
XP_850069
801
87503
S593
L
H
T
P
P
E
S
S
G
C
K
T
L
T
T
Cat
Felis silvestris
Mouse
Mus musculus
P23188
793
86786
S585
L
S
T
P
P
E
S
S
G
C
K
T
L
T
S
Rat
Rattus norvegicus
P23377
793
86635
S585
L
S
A
P
P
E
S
S
G
C
K
T
L
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990046
789
86613
E586
P
G
L
S
N
Q
L
E
S
S
G
C
K
T
L
Frog
Xenopus laevis
P29119
783
86425
D583
L
S
R
K
F
D
G
D
G
S
R
N
V
A
S
Zebra Danio
Brachydanio rerio
NP_001038574
823
89738
Y586
T
D
P
S
V
S
D
Y
T
R
P
S
N
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26016
1269
138609
Y884
Y
Q
Q
I
S
A
T
Y
G
V
I
L
G
K
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P51559
943
103128
Y637
A
Q
S
G
D
P
V
Y
S
A
T
P
A
T
S
Sea Urchin
Strong. purpuratus
XP_780373
746
81468
T550
W
E
F
M
T
T
H
T
W
G
E
N
P
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13134
814
89984
G606
K
T
E
T
F
V
F
G
N
D
K
E
E
V
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.8
93.5
N.A.
93.6
93.6
N.A.
N.A.
79.8
70.2
63.7
N.A.
32.5
N.A.
37.4
48.9
Protein Similarity:
100
99.7
99.2
95
N.A.
95.7
95.2
N.A.
N.A.
86.4
80.8
75
N.A.
42.7
N.A.
50.2
61.2
P-Site Identity:
100
100
93.3
80
N.A.
86.6
86.6
N.A.
N.A.
6.6
20
6.6
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
20
40
13.3
N.A.
20
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
8
0
0
0
8
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
47
0
8
0
0
0
% C
% Asp:
0
8
0
0
8
8
8
8
0
8
0
0
0
0
0
% D
% Glu:
0
8
8
0
0
47
0
8
0
0
8
8
8
0
8
% E
% Phe:
0
0
8
0
16
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
0
0
8
8
62
8
8
0
8
0
8
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
8
0
0
8
0
0
0
0
0
0
54
0
8
8
0
% K
% Leu:
54
0
8
0
0
0
8
0
0
0
0
8
47
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
8
0
0
16
8
8
0
% N
% Pro:
8
24
8
47
47
8
0
0
0
0
8
8
8
0
0
% P
% Gln:
0
16
8
0
0
8
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
8
8
0
0
0
0
% R
% Ser:
0
24
8
16
8
8
47
47
16
16
0
8
0
0
62
% S
% Thr:
8
8
16
8
8
8
8
8
8
0
8
47
0
62
8
% T
% Val:
0
0
16
0
8
8
8
0
0
8
0
0
8
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _