Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FURIN All Species: 22.73
Human Site: S667 Identified Species: 41.67
UniProt: P09958 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09958 NP_002560.1 794 86678 S667 L S C P S H A S L D P V E Q T
Chimpanzee Pan troglodytes XP_510596 794 86649 S667 L S C P S H A S L D P V E Q T
Rhesus Macaque Macaca mulatta XP_001094068 794 86687 S667 L S C P S H A S L D P V E Q T
Dog Lupus familis XP_850069 801 87503 S675 L S C P S H A S L D P V E Q T
Cat Felis silvestris
Mouse Mus musculus P23188 793 86786 S667 L S C P S H A S L D P V E Q T
Rat Rattus norvegicus P23377 793 86635 S667 L S C P S H A S L D P V E Q T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_990046 789 86613 H670 L T C P A H S H F S S L D L S
Frog Xenopus laevis P29119 783 86425 H665 L T C P A H S H Y N L L D Y S
Zebra Danio Brachydanio rerio NP_001038574 823 89738 H674 L S C P P H S H L V A T S C L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26016 1269 138609 A999 S G N G S I K A A K Q V K E S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P51559 943 103128 H761 I D V D N M P H Y D H G K C V
Sea Urchin Strong. purpuratus XP_780373 746 81468 A631 A C L T C Y G A D N G Q C V H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P13134 814 89984 V692 L I G A T F L V L Y F M F F M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.8 93.5 N.A. 93.6 93.6 N.A. N.A. 79.8 70.2 63.7 N.A. 32.5 N.A. 37.4 48.9
Protein Similarity: 100 99.7 99.2 95 N.A. 95.7 95.2 N.A. N.A. 86.4 80.8 75 N.A. 42.7 N.A. 50.2 61.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 26.6 26.6 40 N.A. 13.3 N.A. 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 66.6 73.3 46.6 N.A. 40 N.A. 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 16 0 47 16 8 0 8 0 0 0 0 % A
% Cys: 0 8 70 0 8 0 0 0 0 0 0 0 8 16 0 % C
% Asp: 0 8 0 8 0 0 0 0 8 54 0 0 16 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 47 8 0 % E
% Phe: 0 0 0 0 0 8 0 0 8 0 8 0 8 8 0 % F
% Gly: 0 8 8 8 0 0 8 0 0 0 8 8 0 0 0 % G
% His: 0 0 0 0 0 70 0 31 0 0 8 0 0 0 8 % H
% Ile: 8 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 8 0 0 16 0 0 % K
% Leu: 77 0 8 0 0 0 8 0 62 0 8 16 0 8 8 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 8 % M
% Asn: 0 0 8 0 8 0 0 0 0 16 0 0 0 0 0 % N
% Pro: 0 0 0 70 8 0 8 0 0 0 47 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 8 0 47 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 54 0 0 54 0 24 47 0 8 8 0 8 0 24 % S
% Thr: 0 16 0 8 8 0 0 0 0 0 0 8 0 0 47 % T
% Val: 0 0 8 0 0 0 0 8 0 8 0 54 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 16 8 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _