KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LTA4H
All Species:
20
Human Site:
S416
Identified Species:
36.67
UniProt:
P09960
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09960
NP_000886.1
611
69285
S416
K
A
Y
V
E
K
F
S
Y
K
S
I
T
T
D
Chimpanzee
Pan troglodytes
XP_001145611
585
66392
K400
S
I
T
T
D
D
W
K
D
F
L
Y
S
Y
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539728
676
76153
S481
K
A
Y
V
E
K
F
S
Y
K
S
I
T
T
D
Cat
Felis silvestris
Mouse
Mus musculus
P24527
611
69002
S416
K
A
Y
V
K
K
F
S
Y
Q
S
V
T
T
D
Rat
Rattus norvegicus
P30349
610
69157
S415
K
A
Y
V
E
K
F
S
Y
Q
S
V
T
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509819
759
84771
S564
K
A
Y
V
Q
N
F
S
Y
K
S
V
A
T
D
Chicken
Gallus gallus
NP_001006234
612
69306
A416
K
A
Y
V
Q
Q
F
A
Y
K
S
I
V
T
D
Frog
Xenopus laevis
NP_001085236
609
69001
A412
K
S
Y
I
Q
M
F
A
F
K
S
V
T
T
E
Zebra Danio
Brachydanio rerio
NP_998451
611
69171
A415
K
S
Y
I
Q
L
F
A
Y
G
S
V
T
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500385
625
71291
A421
K
D
Y
L
K
T
F
A
H
Q
A
I
D
S
W
Sea Urchin
Strong. purpuratus
XP_001203105
564
63379
F379
T
T
Q
D
W
K
D
F
L
L
E
Y
F
H
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q10740
671
77334
A461
R
H
Y
F
K
K
F
A
K
K
S
L
D
T
F
Red Bread Mold
Neurospora crassa
Q7S785
614
68982
S414
P
Y
Y
F
G
K
W
S
N
K
S
L
D
S
Y
Conservation
Percent
Protein Identity:
100
95.7
N.A.
85.6
N.A.
92.9
92.8
N.A.
67.7
76.3
67.5
63.8
N.A.
N.A.
N.A.
46.4
53.8
Protein Similarity:
100
95.7
N.A.
88.4
N.A.
97.5
97.2
N.A.
74.8
87.2
82.6
80.8
N.A.
N.A.
N.A.
64.4
68
P-Site Identity:
100
0
N.A.
100
N.A.
80
86.6
N.A.
73.3
73.3
46.6
46.6
N.A.
N.A.
N.A.
26.6
6.6
P-Site Similarity:
100
20
N.A.
100
N.A.
100
100
N.A.
86.6
93.3
93.3
86.6
N.A.
N.A.
N.A.
73.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.6
39.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.7
60.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
47
0
0
0
0
0
39
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
8
8
8
0
8
0
0
0
24
0
47
% D
% Glu:
0
0
0
0
24
0
0
0
0
0
8
0
0
0
24
% E
% Phe:
0
0
0
16
0
0
77
8
8
8
0
0
8
0
16
% F
% Gly:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
0
8
0
16
0
0
0
0
0
0
0
31
0
0
0
% I
% Lys:
70
0
0
0
24
54
0
8
8
54
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
8
0
0
8
8
8
16
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
31
8
0
0
0
24
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
16
0
0
0
0
0
47
0
0
77
0
8
16
0
% S
% Thr:
8
8
8
8
0
8
0
0
0
0
0
0
47
70
0
% T
% Val:
0
0
0
47
0
0
0
0
0
0
0
39
8
0
0
% V
% Trp:
0
0
0
0
8
0
16
0
0
0
0
0
0
0
8
% W
% Tyr:
0
8
85
0
0
0
0
0
54
0
0
16
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _