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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LTA4H
All Species:
26.06
Human Site:
S486
Identified Species:
47.78
UniProt:
P09960
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09960
NP_000886.1
611
69285
S486
A
K
E
D
D
L
N
S
F
N
A
T
D
L
K
Chimpanzee
Pan troglodytes
XP_001145611
585
66392
K467
S
F
N
A
T
D
L
K
D
L
S
S
H
Q
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539728
676
76153
S551
A
K
E
E
D
L
N
S
F
T
A
A
D
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P24527
611
69002
S486
A
K
E
E
D
L
S
S
F
S
I
A
D
L
K
Rat
Rattus norvegicus
P30349
610
69157
S485
A
K
E
E
D
L
N
S
F
S
I
E
D
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509819
759
84771
S634
A
S
E
G
D
L
N
S
F
C
S
A
D
L
K
Chicken
Gallus gallus
NP_001006234
612
69306
S486
A
K
E
S
D
L
G
S
F
S
S
A
D
L
K
Frog
Xenopus laevis
NP_001085236
609
69001
S482
A
T
E
S
D
L
G
S
F
S
A
D
D
V
K
Zebra Danio
Brachydanio rerio
NP_998451
611
69171
S485
A
K
E
A
D
L
A
S
F
T
E
A
D
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500385
625
71291
D491
A
D
E
S
T
V
G
D
I
T
S
E
D
Y
Y
Sea Urchin
Strong. purpuratus
XP_001203105
564
63379
E446
N
F
S
S
S
D
L
E
S
M
S
P
A
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q10740
671
77334
E536
T
T
E
D
F
R
S
E
F
N
A
I
D
I
K
Red Bread Mold
Neurospora crassa
Q7S785
614
68982
S488
K
D
F
T
P
S
P
S
D
V
A
S
W
T
G
Conservation
Percent
Protein Identity:
100
95.7
N.A.
85.6
N.A.
92.9
92.8
N.A.
67.7
76.3
67.5
63.8
N.A.
N.A.
N.A.
46.4
53.8
Protein Similarity:
100
95.7
N.A.
88.4
N.A.
97.5
97.2
N.A.
74.8
87.2
82.6
80.8
N.A.
N.A.
N.A.
64.4
68
P-Site Identity:
100
0
N.A.
80
N.A.
66.6
73.3
N.A.
66.6
66.6
60
60
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
100
20
N.A.
86.6
N.A.
86.6
86.6
N.A.
73.3
80
73.3
66.6
N.A.
N.A.
N.A.
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.6
39.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.7
60.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
0
16
0
0
8
0
0
0
39
39
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
16
0
16
62
16
0
8
16
0
0
8
77
0
0
% D
% Glu:
0
0
77
24
0
0
0
16
0
0
8
16
0
0
0
% E
% Phe:
0
16
8
0
8
0
0
0
70
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
24
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
16
8
0
8
0
% I
% Lys:
8
47
0
0
0
0
0
8
0
0
0
0
0
0
77
% K
% Leu:
0
0
0
0
0
62
16
0
0
8
0
0
0
47
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
31
0
0
16
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
8
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
8
31
8
8
16
70
8
31
39
16
0
0
0
% S
% Thr:
8
16
0
8
16
0
0
0
0
24
0
8
0
8
0
% T
% Val:
0
0
0
0
0
8
0
0
0
8
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _