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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALDOC All Species: 36.36
Human Site: Y204 Identified Species: 61.54
UniProt: P09972 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P09972 NP_005156.1 364 39456 Y204 H D L K R C Q Y V T E K V L A
Chimpanzee Pan troglodytes Q5R1X4 364 39508 Y204 H D L K R C Q Y V T E K V L A
Rhesus Macaque Macaca mulatta XP_001107579 364 39417 Y204 H D L K R C Q Y V T E K V L A
Dog Lupus familis XP_537742 364 39323 Y204 H D L K R C Q Y V T E K V L A
Cat Felis silvestris
Mouse Mus musculus P05063 363 39376 Y204 H D L K R C Q Y V T E K V L A
Rat Rattus norvegicus P09117 363 39265 F204 H D L K R C Q F V T E K V L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508559 364 39349 Y204 H D L K R C Q Y V T E K V L A
Chicken Gallus gallus P07341 364 39277 Y204 H D L Q R C Q Y V T E K V L A
Frog Xenopus laevis NP_001080387 364 39254 Y204 H D L K R C Q Y I T E K V L A
Zebra Danio Brachydanio rerio Q8JH70 363 39241 Y204 H D L K R C Q Y V T E K V L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07764 361 39029 Q203 D H D L D R A Q K V T E T V L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54216 366 39222 I206 C L A R G Q K I T E T V L S Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P08440 355 38586 A198 P H D I D R C A Y V T E T V L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P22197 358 38792 A198 S H D I K K C A A V T E T V L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 99.4 98.6 N.A. 97.5 96.6 N.A. 92.3 73 84.3 84.6 N.A. 69.5 N.A. 64.2 N.A.
Protein Similarity: 100 99.4 99.4 99.4 N.A. 98.9 98.9 N.A. 95.3 83.5 91.2 90.1 N.A. 78.8 N.A. 75.6 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. 100 93.3 93.3 100 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 13.3 N.A. 20 N.A.
Percent
Protein Identity: N.A. 57.1 N.A. 55.2 N.A. N.A.
Protein Similarity: N.A. 68.4 N.A. 68.6 N.A. N.A.
P-Site Identity: N.A. 0 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 13.3 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 8 15 8 0 0 0 0 0 72 % A
% Cys: 8 0 0 0 0 72 15 0 0 0 0 0 0 0 0 % C
% Asp: 8 72 22 0 15 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 72 22 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % G
% His: 72 22 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 15 0 0 0 8 8 0 0 0 0 0 0 % I
% Lys: 0 0 0 65 8 8 8 0 8 0 0 72 0 0 0 % K
% Leu: 0 8 72 8 0 0 0 0 0 0 0 0 8 72 22 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 8 72 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 72 15 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 8 72 29 0 22 0 0 % T
% Val: 0 0 0 0 0 0 0 0 65 22 0 8 72 22 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 65 8 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _