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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C4A All Species: 19.09
Human Site: Y1560 Identified Species: 52.5
UniProt: P0C0L4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C0L4 NP_009224.2 1744 192771 Y1560 S A T L Y D Y Y N P E R R C S
Chimpanzee Pan troglodytes XP_001162503 1744 192821 Y1560 S A T L Y D Y Y N P E R R C S
Rhesus Macaque Macaca mulatta XP_001117272 1052 115714 Q886 A G G G G L A Q Q V L V P A G
Dog Lupus familis XP_538843 1587 174795 L1421 G A P T R S K L L S T L C S A
Cat Felis silvestris
Mouse Mus musculus P01029 1738 192867 Y1554 S A V L Y D Y Y S P D H K C S
Rat Rattus norvegicus P08649 1737 192144 Y1553 S A V L Y D Y Y S P D H K C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505969 1653 185840 Y1473 S V K V Y S Y Y N L E E S C T
Chicken Gallus gallus P20740 1473 166336 P1307 Q T P L P Q V P G K Y S L T V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694622 1697 190715 Y1512 S A V I Y D Y Y S P E K R C G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 57.9 72.9 N.A. 76.4 79.6 N.A. 30.5 21.5 N.A. 34 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.3 58.9 79.5 N.A. 86.7 88.8 N.A. 50.4 40 N.A. 55 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 6.6 N.A. 66.6 66.6 N.A. 46.6 6.6 N.A. 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 13.3 N.A. 86.6 86.6 N.A. 60 6.6 N.A. 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 67 0 0 0 0 12 0 0 0 0 0 0 12 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 12 67 0 % C
% Asp: 0 0 0 0 0 56 0 0 0 0 23 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 45 12 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 12 12 12 12 12 0 0 0 12 0 0 0 0 0 23 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 23 0 0 0 % H
% Ile: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 12 0 0 0 12 0 0 12 0 12 23 0 0 % K
% Leu: 0 0 0 56 0 12 0 12 12 12 12 12 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 34 0 0 0 0 0 0 % N
% Pro: 0 0 23 0 12 0 0 12 0 56 0 0 12 0 0 % P
% Gln: 12 0 0 0 0 12 0 12 12 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 12 0 0 0 0 0 0 23 34 0 0 % R
% Ser: 67 0 0 0 0 23 0 0 34 12 0 12 12 12 45 % S
% Thr: 0 12 23 12 0 0 0 0 0 0 12 0 0 12 12 % T
% Val: 0 12 34 12 0 0 12 0 0 12 0 12 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 67 0 67 67 0 0 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _