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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C4B
All Species:
12.42
Human Site:
Y251
Identified Species:
34.17
UniProt:
P0C0L5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C0L5
NP_001002029.3
1744
192793
Y251
K
I
T
P
G
K
P
Y
I
L
T
V
P
G
H
Chimpanzee
Pan troglodytes
XP_001162420
1744
192839
Y251
K
I
T
P
G
K
P
Y
I
L
T
V
P
G
H
Rhesus Macaque
Macaca mulatta
XP_001117272
1052
115714
Dog
Lupus familis
XP_538843
1587
174795
K202
Q
C
H
I
S
L
S
K
A
E
V
R
G
A
L
Cat
Felis silvestris
Mouse
Mus musculus
P01029
1738
192867
Y249
K
I
T
P
W
K
P
Y
I
L
M
V
P
S
N
Rat
Rattus norvegicus
P08649
1737
192144
Y249
K
L
T
P
W
K
P
Y
I
L
T
V
P
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505969
1653
185840
D243
E
K
F
Y
Y
I
D
D
P
E
G
L
S
V
D
Chicken
Gallus gallus
P20740
1473
166336
K88
I
N
T
T
I
F
E
K
N
T
T
T
S
N
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694622
1697
190715
S243
Q
P
Y
H
I
L
M
S
E
S
F
P
F
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
57.9
72.8
N.A.
76.4
79.6
N.A.
30.6
21.5
N.A.
33.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
58.9
79.5
N.A.
86.6
88.8
N.A.
50.5
40
N.A.
54.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
73.3
73.3
N.A.
0
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
6.6
N.A.
80
86.6
N.A.
13.3
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
12
% D
% Glu:
12
0
0
0
0
0
12
0
12
23
0
0
0
0
0
% E
% Phe:
0
0
12
0
0
12
0
0
0
0
12
0
12
0
0
% F
% Gly:
0
0
0
0
23
0
0
0
0
0
12
0
12
23
12
% G
% His:
0
0
12
12
0
0
0
0
0
0
0
0
0
0
23
% H
% Ile:
12
34
0
12
23
12
0
0
45
0
0
0
0
0
12
% I
% Lys:
45
12
0
0
0
45
0
23
0
0
0
0
0
0
0
% K
% Leu:
0
12
0
0
0
23
0
0
0
45
0
12
0
0
12
% L
% Met:
0
0
0
0
0
0
12
0
0
0
12
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
12
0
0
0
0
23
12
% N
% Pro:
0
12
0
45
0
0
45
0
12
0
0
12
45
0
0
% P
% Gln:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% R
% Ser:
0
0
0
0
12
0
12
12
0
12
0
0
23
23
0
% S
% Thr:
0
0
56
12
0
0
0
0
0
12
45
12
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
12
45
0
12
0
% V
% Trp:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
12
12
0
0
45
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _