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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: H2AFZ All Species: 46.36
Human Site: S43 Identified Species: 63.75
UniProt: P0C0S5 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C0S5 NP_002097.1 128 13553 S43 H L K S R T T S H G R V G A T
Chimpanzee Pan troglodytes XP_517363 398 42541 S313 H L K S R T T S H G R V G A T
Rhesus Macaque Macaca mulatta XP_001093992 314 32755 S229 H L K T R T T S H G R V G A T
Dog Lupus familis XP_535390 128 13460 S43 H L K S R T T S H G R V G A T
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus P02262 130 14059 Y40 R L L R K G N Y A E R V G A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507614 252 26680 S167 H L K T R T T S H G R V G A T
Chicken Gallus gallus Q5ZMD6 128 13564 S43 H L K S R T T S H G R V G A T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001036788 128 13548 S43 H L K T R T T S H G R V G A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08985 141 14963 S43 H L K S R T T S H G R V G A T
Honey Bee Apis mellifera XP_624167 155 16370 S70 H L K N R T T S H G R V G A T
Nematode Worm Caenorhab. elegans Q27511 140 14651 S45 F L K Q R T T S S G R V G A T
Sea Urchin Strong. purpuratus P08991 125 13146 S40 H L K N R T T S H G R V G A T
Poplar Tree Populus trichocarpa XP_002324843 134 14268 R49 I H R L L K S R A T A H G R V
Maize Zea mays NP_001141633 138 14579 I46 L Q F P V G R I H R Q L K S R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23628 136 14522 R51 I H R Q L K T R V S A H G R V
Baker's Yeast Sacchar. cerevisiae Q12692 134 14264 G48 Y L K R H A T G R T R V G S K
Red Bread Mold Neurospora crassa Q873G4 143 15269 N53 F L K Q N T Q N K M R V G A K
Conservation
Percent
Protein Identity: 100 31.9 39.8 90.6 N.A. N.A. 60.7 N.A. 49.5 99.2 N.A. 99.2 N.A. 87.2 78.7 79.2 92.9
Protein Similarity: 100 31.9 40.1 91.4 N.A. N.A. 71.5 N.A. 50 99.2 N.A. 100 N.A. 87.9 79.3 82.8 93.7
P-Site Identity: 100 100 93.3 100 N.A. N.A. 33.3 N.A. 93.3 100 N.A. 93.3 N.A. 100 93.3 80 93.3
P-Site Similarity: 100 100 100 100 N.A. N.A. 40 N.A. 100 100 N.A. 100 N.A. 100 100 80 100
Percent
Protein Identity: 79.1 78.2 N.A. 75.7 63.4 62.2
Protein Similarity: 81.3 81.1 N.A. 81.6 76.1 72
P-Site Identity: 6.6 6.6 N.A. 13.3 40 46.6
P-Site Similarity: 20 26.6 N.A. 20 53.3 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 6 0 0 12 0 12 0 0 77 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % E
% Phe: 12 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 12 0 6 0 65 0 0 95 0 6 % G
% His: 59 12 0 0 6 0 0 0 65 0 0 12 0 0 0 % H
% Ile: 12 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % I
% Lys: 0 0 77 0 6 12 0 0 6 0 0 0 6 0 12 % K
% Leu: 6 83 6 6 12 0 0 0 0 0 0 6 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % M
% Asn: 0 0 0 12 6 0 6 6 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 6 0 18 0 0 6 0 0 0 6 0 0 0 0 % Q
% Arg: 6 0 12 12 65 0 6 12 6 6 83 0 0 12 6 % R
% Ser: 0 0 0 30 0 0 6 65 6 6 0 0 0 12 0 % S
% Thr: 0 0 0 18 0 71 77 0 0 12 0 0 0 0 65 % T
% Val: 0 0 0 0 6 0 0 0 6 0 0 83 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _