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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: H2AFZ All Species: 49.7
Human Site: T83 Identified Species: 68.33
UniProt: P0C0S5 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C0S5 NP_002097.1 128 13553 T83 D L K V K R I T P R H L Q L A
Chimpanzee Pan troglodytes XP_517363 398 42541 T353 D L K V K R I T P R H L Q L A
Rhesus Macaque Macaca mulatta XP_001093992 314 32755 T269 D L K V K R I T P R H L Q L A
Dog Lupus familis XP_535390 128 13460 I83 D L K V K C I I S R H L Q L A
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus P02262 130 14059 I80 D N K K T R I I P R H L Q L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507614 252 26680 T207 D L K V K R I T P R H L Q L A
Chicken Gallus gallus Q5ZMD6 128 13564 T83 D L K V K R I T P R H L Q L A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001036788 128 13548 T83 D L K V K R I T P R H L Q L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08985 141 14963 T83 D L K V K R I T P R H L Q L A
Honey Bee Apis mellifera XP_624167 155 16370 T110 D L K V K R I T P R H L Q L A
Nematode Worm Caenorhab. elegans Q27511 140 14651 T85 D L K V K R I T P R H L H L A
Sea Urchin Strong. purpuratus P08991 125 13146 T80 D L K V K R I T P R H L Q L A
Poplar Tree Populus trichocarpa XP_002324843 134 14268 K89 A S K D L K V K R I T P R H L
Maize Zea mays NP_001141633 138 14579 A86 V L E L A G N A S K D L K V K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23628 136 14522 K91 A S K D L K V K R I T P R H L
Baker's Yeast Sacchar. cerevisiae Q12692 134 14264 T88 D L K V K R I T P R H L Q L A
Red Bread Mold Neurospora crassa Q873G4 143 15269 T93 D L K V K R I T P R H L Q L A
Conservation
Percent
Protein Identity: 100 31.9 39.8 90.6 N.A. N.A. 60.7 N.A. 49.5 99.2 N.A. 99.2 N.A. 87.2 78.7 79.2 92.9
Protein Similarity: 100 31.9 40.1 91.4 N.A. N.A. 71.5 N.A. 50 99.2 N.A. 100 N.A. 87.9 79.3 82.8 93.7
P-Site Identity: 100 100 100 80 N.A. N.A. 73.3 N.A. 100 100 N.A. 100 N.A. 100 100 93.3 100
P-Site Similarity: 100 100 100 80 N.A. N.A. 73.3 N.A. 100 100 N.A. 100 N.A. 100 100 93.3 100
Percent
Protein Identity: 79.1 78.2 N.A. 75.7 63.4 62.2
Protein Similarity: 81.3 81.1 N.A. 81.6 76.1 72
P-Site Identity: 6.6 13.3 N.A. 6.6 100 100
P-Site Similarity: 26.6 46.6 N.A. 26.6 100 100
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 6 0 0 6 0 0 0 0 0 0 83 % A
% Cys: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % C
% Asp: 83 0 0 12 0 0 0 0 0 0 6 0 0 0 0 % D
% Glu: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 83 0 6 12 0 % H
% Ile: 0 0 0 0 0 0 83 12 0 12 0 0 0 0 0 % I
% Lys: 0 0 95 6 77 12 0 12 0 6 0 0 6 0 6 % K
% Leu: 0 83 0 6 12 0 0 0 0 0 0 89 0 83 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 6 0 0 0 0 6 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 77 0 0 12 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 77 0 0 % Q
% Arg: 0 0 0 0 0 77 0 0 12 83 0 0 12 0 0 % R
% Ser: 0 12 0 0 0 0 0 0 12 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 6 0 0 71 0 0 12 0 0 0 0 % T
% Val: 6 0 0 77 0 0 12 0 0 0 0 0 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _