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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WEE2
All Species:
7.27
Human Site:
S130
Identified Species:
13.33
UniProt:
P0C1S8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C1S8
NP_001099028.1
567
62925
S130
S
P
T
G
K
L
P
S
R
G
P
K
H
L
K
Chimpanzee
Pan troglodytes
XP_519504
455
50573
E46
N
I
N
P
F
T
P
E
S
Y
K
K
L
F
L
Rhesus Macaque
Macaca mulatta
NP_001099016
568
63102
S130
S
P
T
G
K
L
P
S
R
G
P
K
H
L
K
Dog
Lupus familis
XP_532748
515
57465
V106
P
D
S
R
S
E
V
V
H
C
E
S
P
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
Q66JT0
555
62324
S124
S
L
L
E
K
L
S
S
R
S
S
R
H
M
R
Rat
Rattus norvegicus
Q63802
646
71478
L208
I
D
S
S
S
V
K
L
R
G
S
S
L
F
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520344
429
47032
C20
E
E
G
V
W
R
G
C
Q
V
P
A
S
V
T
Chicken
Gallus gallus
NP_001026352
641
70947
A146
G
R
S
P
P
H
P
A
A
G
G
C
R
L
R
Frog
Xenopus laevis
P47817
555
61670
C122
S
P
G
S
R
V
H
C
R
G
Q
R
L
L
R
Zebra Danio
Brachydanio rerio
NP_001032299
527
59094
I118
E
R
V
P
S
V
N
I
N
P
F
T
P
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54350
609
68790
P147
S
E
R
P
R
S
L
P
L
H
N
R
K
L
P
Honey Bee
Apis mellifera
XP_624069
589
66032
N168
D
K
P
T
A
N
V
N
P
F
T
P
N
G
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999796
624
68925
N137
P
P
H
K
R
L
R
N
L
K
L
F
D
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.7
94.3
71.9
N.A.
66.8
43
N.A.
47.7
42.1
52.9
43.5
N.A.
33.5
36.1
N.A.
39.2
Protein Similarity:
100
78.1
95.9
77.7
N.A.
76.5
56.8
N.A.
57.1
57.8
64.9
58.9
N.A.
50.7
52.6
N.A.
55.2
P-Site Identity:
100
13.3
100
0
N.A.
40
13.3
N.A.
6.6
20
33.3
0
N.A.
13.3
0
N.A.
13.3
P-Site Similarity:
100
20
100
6.6
N.A.
60
26.6
N.A.
20
40
60
6.6
N.A.
26.6
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
8
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
16
0
8
0
8
0
0
0
% C
% Asp:
8
16
0
0
0
0
0
0
0
0
0
0
8
8
0
% D
% Glu:
16
16
0
8
0
8
0
8
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
8
8
8
0
16
0
% F
% Gly:
8
0
16
16
0
0
8
0
0
39
8
0
0
8
0
% G
% His:
0
0
8
0
0
8
8
0
8
8
0
0
24
0
0
% H
% Ile:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
8
24
0
8
0
0
8
8
24
8
0
16
% K
% Leu:
0
8
8
0
0
31
8
8
16
0
8
0
24
39
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
16
% M
% Asn:
8
0
8
0
0
8
8
16
8
0
8
0
8
0
0
% N
% Pro:
16
31
8
31
8
0
31
8
8
8
24
8
16
0
16
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% Q
% Arg:
0
16
8
8
24
8
8
0
39
0
0
24
8
0
24
% R
% Ser:
39
0
24
16
24
8
8
24
8
8
16
16
8
8
0
% S
% Thr:
0
0
16
8
0
8
0
0
0
0
8
8
0
0
24
% T
% Val:
0
0
8
8
0
24
16
8
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _