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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WEE2
All Species:
5.76
Human Site:
S251
Identified Species:
10.56
UniProt:
P0C1S8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C1S8
NP_001099028.1
567
62925
S251
M
K
T
F
T
E
L
S
N
E
N
S
A
L
H
Chimpanzee
Pan troglodytes
XP_519504
455
50573
V148
E
N
S
A
L
H
E
V
Y
A
H
A
V
L
G
Rhesus Macaque
Macaca mulatta
NP_001099016
568
63102
S252
M
K
T
F
A
E
L
S
N
E
N
L
A
L
H
Dog
Lupus familis
XP_532748
515
57465
A208
V
L
R
E
T
N
M
A
S
R
Y
E
K
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q66JT0
555
62324
L246
S
A
K
S
F
S
G
L
S
N
E
L
D
L
H
Rat
Rattus norvegicus
Q63802
646
71478
V337
K
K
P
L
A
G
S
V
D
E
Q
N
A
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520344
429
47032
E122
N
E
L
A
A
L
R
E
V
Y
A
H
A
V
L
Chicken
Gallus gallus
NP_001026352
641
70947
V334
K
K
P
L
A
G
S
V
D
E
Q
N
A
L
R
Frog
Xenopus laevis
P47817
555
61670
G247
R
S
K
K
P
L
A
G
S
T
D
E
Q
L
A
Zebra Danio
Brachydanio rerio
NP_001032299
527
59094
G220
R
S
R
R
P
I
A
G
S
A
N
E
Q
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54350
609
68790
S278
K
K
P
V
A
G
S
S
F
E
K
R
A
L
N
Honey Bee
Apis mellifera
XP_624069
589
66032
I272
I
K
P
V
A
G
S
I
N
E
K
N
A
L
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999796
624
68925
P262
D
G
S
Y
T
E
N
P
A
K
R
I
A
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.7
94.3
71.9
N.A.
66.8
43
N.A.
47.7
42.1
52.9
43.5
N.A.
33.5
36.1
N.A.
39.2
Protein Similarity:
100
78.1
95.9
77.7
N.A.
76.5
56.8
N.A.
57.1
57.8
64.9
58.9
N.A.
50.7
52.6
N.A.
55.2
P-Site Identity:
100
6.6
86.6
6.6
N.A.
13.3
26.6
N.A.
6.6
26.6
6.6
13.3
N.A.
33.3
33.3
N.A.
26.6
P-Site Similarity:
100
26.6
86.6
33.3
N.A.
20
40
N.A.
20
40
20
20
N.A.
40
53.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
16
47
0
16
8
8
16
8
8
62
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
16
0
8
0
8
0
0
% D
% Glu:
8
8
0
8
0
24
8
8
0
47
8
24
0
8
0
% E
% Phe:
0
0
0
16
8
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
0
8
0
0
0
31
8
16
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
24
% H
% Ile:
8
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% I
% Lys:
24
47
16
8
0
0
0
0
0
8
16
0
8
0
0
% K
% Leu:
0
8
8
16
8
16
16
8
0
0
0
16
0
85
8
% L
% Met:
16
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
8
8
0
24
8
24
24
0
0
16
% N
% Pro:
0
0
31
0
16
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
16
0
16
0
0
% Q
% Arg:
16
0
16
8
0
0
8
0
0
8
8
8
0
0
24
% R
% Ser:
8
16
16
8
0
8
31
24
31
0
0
8
0
0
0
% S
% Thr:
0
0
16
0
24
0
0
0
0
8
0
0
0
0
0
% T
% Val:
8
0
0
16
0
0
0
24
8
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
8
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _