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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WEE2 All Species: 9.09
Human Site: S456 Identified Species: 16.67
UniProt: P0C1S8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P0C1S8 NP_001099028.1 567 62925 S456 P D V P Q E L S E S F S S L L
Chimpanzee Pan troglodytes XP_519504 455 50573 E345 D V P Q E L S E S F S S L L K
Rhesus Macaque Macaca mulatta NP_001099016 568 63102 S457 P D V P Q E L S E S F S S L L
Dog Lupus familis XP_532748 515 57465 N405 G D S R F L A N E I L Q E D Y
Cat Felis silvestris
Mouse Mus musculus Q66JT0 555 62324 E445 I R K G N F P E I S Q E L S D
Rat Rattus norvegicus Q63802 646 71478 V536 R L P R I P Q V L S Q E L T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520344 429 47032 S319 P P I P Q R L S E D F Y N L L
Chicken Gallus gallus NP_001026352 641 70947 P531 Q G K L P R I P Q V L S Q E L
Frog Xenopus laevis P47817 555 61670 V445 R K G N L P H V P Q L L T P V
Zebra Danio Brachydanio rerio NP_001032299 527 59094 L417 H R L R Q G E L P N L P H E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54350 609 68790 R488 P I L P S L S R D F N E L I A
Honey Bee Apis mellifera XP_624069 589 66032 S477 L K E L S H Y S R D L N E L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999796 624 68925 L497 A D I F A L A L T A Y L A A G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.7 94.3 71.9 N.A. 66.8 43 N.A. 47.7 42.1 52.9 43.5 N.A. 33.5 36.1 N.A. 39.2
Protein Similarity: 100 78.1 95.9 77.7 N.A. 76.5 56.8 N.A. 57.1 57.8 64.9 58.9 N.A. 50.7 52.6 N.A. 55.2
P-Site Identity: 100 13.3 100 13.3 N.A. 6.6 6.6 N.A. 60 13.3 0 13.3 N.A. 13.3 20 N.A. 6.6
P-Site Similarity: 100 20 100 20 N.A. 6.6 6.6 N.A. 73.3 26.6 13.3 26.6 N.A. 33.3 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 16 0 0 8 0 0 8 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 31 0 0 0 0 0 0 8 16 0 0 0 8 8 % D
% Glu: 0 0 8 0 8 16 8 16 31 0 0 24 16 16 8 % E
% Phe: 0 0 0 8 8 8 0 0 0 16 24 0 0 0 0 % F
% Gly: 8 8 8 8 0 8 0 0 0 0 0 0 0 0 8 % G
% His: 8 0 0 0 0 8 8 0 0 0 0 0 8 0 0 % H
% Ile: 8 8 16 0 8 0 8 0 8 8 0 0 0 8 0 % I
% Lys: 0 16 16 0 0 0 0 0 0 0 0 0 0 0 8 % K
% Leu: 8 8 16 16 8 31 24 16 8 0 39 16 31 39 47 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 8 0 0 8 0 8 8 8 8 0 0 % N
% Pro: 31 8 16 31 8 16 8 8 16 0 0 8 0 8 0 % P
% Gln: 8 0 0 8 31 0 8 0 8 8 16 8 8 0 0 % Q
% Arg: 16 16 0 24 0 16 0 8 8 0 0 0 0 0 0 % R
% Ser: 0 0 8 0 16 0 16 31 8 31 8 31 16 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 8 0 0 0 8 8 0 % T
% Val: 0 8 16 0 0 0 0 16 0 8 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 8 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _