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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WEE2
All Species:
2.73
Human Site:
S541
Identified Species:
5
UniProt:
P0C1S8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C1S8
NP_001099028.1
567
62925
S541
V
S
G
T
H
T
G
S
R
S
T
K
R
L
V
Chimpanzee
Pan troglodytes
XP_519504
455
50573
R430
S
G
T
H
T
G
S
R
S
T
K
R
L
V
G
Rhesus Macaque
Macaca mulatta
NP_001099016
568
63102
P542
V
S
G
T
H
T
G
P
R
S
T
K
R
L
V
Dog
Lupus familis
XP_532748
515
57465
R490
L
A
R
S
R
V
L
R
P
S
L
R
K
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q66JT0
555
62324
C530
H
H
C
Y
Y
Q
I
C
K
G
S
R
H
L
L
Rat
Rattus norvegicus
Q63802
646
71478
R621
L
T
D
R
M
A
T
R
S
T
T
Q
S
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520344
429
47032
P404
P
S
A
P
R
A
A
P
A
R
P
K
G
S
R
Chicken
Gallus gallus
NP_001026352
641
70947
T616
L
F
T
D
R
M
T
T
R
S
T
T
Q
S
R
Frog
Xenopus laevis
P47817
555
61670
G530
S
D
L
P
P
M
S
G
F
S
C
R
G
R
K
Zebra Danio
Brachydanio rerio
NP_001032299
527
59094
G502
P
Q
Q
S
C
Q
P
G
S
L
P
K
A
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54350
609
68790
D573
T
N
N
P
D
S
L
D
G
Q
R
C
L
R
S
Honey Bee
Apis mellifera
XP_624069
589
66032
Y562
N
T
M
N
A
G
G
Y
K
L
R
P
T
P
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999796
624
68925
N582
L
N
V
A
K
F
Q
N
A
I
L
S
R
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.7
94.3
71.9
N.A.
66.8
43
N.A.
47.7
42.1
52.9
43.5
N.A.
33.5
36.1
N.A.
39.2
Protein Similarity:
100
78.1
95.9
77.7
N.A.
76.5
56.8
N.A.
57.1
57.8
64.9
58.9
N.A.
50.7
52.6
N.A.
55.2
P-Site Identity:
100
0
93.3
6.6
N.A.
6.6
6.6
N.A.
13.3
20
6.6
6.6
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
20
93.3
40
N.A.
40
33.3
N.A.
13.3
40
13.3
13.3
N.A.
13.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
8
16
8
0
16
0
0
0
8
8
0
% A
% Cys:
0
0
8
0
8
0
0
8
0
0
8
8
0
0
0
% C
% Asp:
0
8
8
8
8
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% E
% Phe:
0
8
0
0
0
8
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
8
16
0
0
16
24
16
8
8
0
0
16
0
8
% G
% His:
8
8
0
8
16
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
16
0
8
31
8
8
8
% K
% Leu:
31
0
8
0
0
0
16
0
0
16
16
0
16
24
16
% L
% Met:
0
0
8
0
8
16
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
16
8
8
0
0
0
8
0
0
0
0
0
8
0
% N
% Pro:
16
0
0
24
8
0
8
16
8
0
16
8
0
8
0
% P
% Gln:
0
8
8
0
0
16
8
0
0
8
0
8
8
0
0
% Q
% Arg:
0
0
8
8
24
0
0
24
24
8
16
31
24
16
31
% R
% Ser:
16
24
0
16
0
8
16
8
24
39
8
8
8
16
8
% S
% Thr:
8
16
16
16
8
16
16
8
0
16
31
8
8
0
8
% T
% Val:
16
0
8
0
0
8
0
0
0
0
0
0
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _