KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WEE2
All Species:
11.21
Human Site:
T139
Identified Species:
20.56
UniProt:
P0C1S8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C1S8
NP_001099028.1
567
62925
T139
G
P
K
H
L
K
L
T
P
A
P
L
K
D
E
Chimpanzee
Pan troglodytes
XP_519504
455
50573
S55
Y
K
K
L
F
L
Q
S
G
G
K
R
K
I
R
Rhesus Macaque
Macaca mulatta
NP_001099016
568
63102
T139
G
P
K
H
L
K
L
T
P
A
P
L
K
D
E
Dog
Lupus familis
XP_532748
515
57465
K115
C
E
S
P
Y
T
P
K
S
L
L
S
Q
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q66JT0
555
62324
T133
S
S
R
H
M
R
L
T
P
A
S
L
M
D
E
Rat
Rattus norvegicus
Q63802
646
71478
T217
G
S
S
L
F
M
D
T
E
K
S
G
K
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520344
429
47032
D29
V
P
A
S
V
T
C
D
T
K
I
G
L
E
S
Chicken
Gallus gallus
NP_001026352
641
70947
D155
G
G
C
R
L
R
G
D
E
P
G
S
P
L
P
Frog
Xenopus laevis
P47817
555
61670
V131
G
Q
R
L
L
R
F
V
A
G
T
G
A
E
L
Zebra Danio
Brachydanio rerio
NP_001032299
527
59094
R127
P
F
T
P
D
T
V
R
R
N
S
E
H
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54350
609
68790
Q156
H
N
R
K
L
P
T
Q
D
T
A
N
V
N
P
Honey Bee
Apis mellifera
XP_624069
589
66032
L177
F
T
P
N
G
M
L
L
T
A
R
K
R
T
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999796
624
68925
T146
K
L
F
D
S
P
H
T
P
K
S
L
I
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.7
94.3
71.9
N.A.
66.8
43
N.A.
47.7
42.1
52.9
43.5
N.A.
33.5
36.1
N.A.
39.2
Protein Similarity:
100
78.1
95.9
77.7
N.A.
76.5
56.8
N.A.
57.1
57.8
64.9
58.9
N.A.
50.7
52.6
N.A.
55.2
P-Site Identity:
100
13.3
100
0
N.A.
53.3
26.6
N.A.
6.6
13.3
13.3
0
N.A.
6.6
13.3
N.A.
20
P-Site Similarity:
100
20
100
6.6
N.A.
73.3
26.6
N.A.
20
20
33.3
13.3
N.A.
20
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
8
31
8
0
8
0
0
% A
% Cys:
8
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
8
16
8
0
0
0
0
24
0
% D
% Glu:
0
8
0
0
0
0
0
0
16
0
0
8
0
16
31
% E
% Phe:
8
8
8
0
16
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
39
8
0
0
8
0
8
0
8
16
8
24
0
0
0
% G
% His:
8
0
0
24
0
0
8
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
8
8
0
% I
% Lys:
8
8
24
8
0
16
0
8
0
24
8
8
31
0
16
% K
% Leu:
0
8
0
24
39
8
31
8
0
8
8
31
8
8
8
% L
% Met:
0
0
0
0
8
16
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
8
0
0
0
0
0
8
0
8
0
8
0
% N
% Pro:
8
24
8
16
0
16
8
0
31
8
16
0
8
0
16
% P
% Gln:
0
8
0
0
0
0
8
8
0
0
0
0
8
8
0
% Q
% Arg:
0
0
24
8
0
24
0
8
8
0
8
8
8
8
16
% R
% Ser:
8
16
16
8
8
0
0
8
8
0
31
16
0
8
8
% S
% Thr:
0
8
8
0
0
24
8
39
16
8
8
0
0
8
0
% T
% Val:
8
0
0
0
8
0
8
8
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _