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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WEE2
All Species:
4.24
Human Site:
T435
Identified Species:
7.78
UniProt:
P0C1S8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C1S8
NP_001099028.1
567
62925
T435
A
G
A
E
S
L
P
T
N
G
A
A
W
H
H
Chimpanzee
Pan troglodytes
XP_519504
455
50573
H330
T
N
G
A
A
W
H
H
I
R
K
G
N
F
P
Rhesus Macaque
Macaca mulatta
NP_001099016
568
63102
T436
A
G
A
E
S
L
P
T
N
G
T
A
W
H
H
Dog
Lupus familis
XP_532748
515
57465
I390
D
L
G
H
V
T
S
I
S
K
P
K
V
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q66JT0
555
62324
I430
A
G
A
E
S
L
P
I
N
G
D
M
W
H
H
Rat
Rattus norvegicus
Q63802
646
71478
Q521
P
L
P
R
N
G
D
Q
W
H
E
I
R
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520344
429
47032
H304
P
L
N
G
T
S
W
H
H
I
R
Q
G
N
L
Chicken
Gallus gallus
NP_001026352
641
70947
G516
A
E
P
L
P
T
N
G
D
Q
W
H
E
I
R
Frog
Xenopus laevis
P47817
555
61670
C429
A
G
A
A
P
L
P
C
N
E
D
S
W
H
H
Zebra Danio
Brachydanio rerio
NP_001032299
527
59094
L402
L
A
A
G
A
S
P
L
P
Q
N
G
D
D
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54350
609
68790
K467
A
G
G
G
P
L
P
K
N
G
P
E
W
H
N
Honey Bee
Apis mellifera
XP_624069
589
66032
K457
G
G
G
G
P
L
P
K
N
G
P
E
W
H
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999796
624
68925
D455
S
L
I
Y
K
I
G
D
L
G
H
V
T
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.7
94.3
71.9
N.A.
66.8
43
N.A.
47.7
42.1
52.9
43.5
N.A.
33.5
36.1
N.A.
39.2
Protein Similarity:
100
78.1
95.9
77.7
N.A.
76.5
56.8
N.A.
57.1
57.8
64.9
58.9
N.A.
50.7
52.6
N.A.
55.2
P-Site Identity:
100
0
93.3
0
N.A.
80
0
N.A.
0
6.6
60
13.3
N.A.
53.3
46.6
N.A.
6.6
P-Site Similarity:
100
6.6
93.3
6.6
N.A.
80
6.6
N.A.
20
13.3
66.6
20
N.A.
60
46.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
8
39
16
16
0
0
0
0
0
8
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
8
8
0
16
0
8
8
8
% D
% Glu:
0
8
0
24
0
0
0
0
0
8
8
16
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
47
31
31
0
8
8
8
0
47
0
16
8
0
8
% G
% His:
0
0
0
8
0
0
8
16
8
8
8
8
0
47
31
% H
% Ile:
0
0
8
0
0
8
0
16
8
8
0
8
0
8
8
% I
% Lys:
0
0
0
0
8
0
0
16
0
8
8
8
0
0
0
% K
% Leu:
8
31
0
8
0
47
0
8
8
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
8
0
8
0
8
0
47
0
8
0
8
8
8
% N
% Pro:
16
0
16
0
31
0
54
0
8
0
24
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
8
0
16
0
8
0
8
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
8
8
0
8
0
8
% R
% Ser:
8
0
0
0
24
16
8
0
8
0
0
8
0
8
0
% S
% Thr:
8
0
0
0
8
16
0
16
0
0
8
0
8
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
8
8
0
8
0
8
0
47
0
8
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _